Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Case Report Volume 5 Issue 11

Galactorrhea, Amenorrhea and Extrapyramidal Side Effects with Low Doses of Amisulprideg

Padmaraj B Patil

Consultant Psychiatrist Kamala Hospital, Kolhapur, Maharastra, India

*Corresponding Author: Padmaraj B Patil, Consultant Psychiatrist Kamala Hospital, Kolhapur, Maharastra, India.

Received: July 12, 2022; Published: October 07, 2022

Abstract

In India, amisulpride comparatively new antipsychotic which is claimed to be effective in both positive and negative symptoms schizophrenia and other disorder even though it has little or no action on serotonergic receptors. Lower striatal dopaminergic receptor binding capacity and limbic selectivity causes of EPS. But, in clinical practice, we are getting EPS with this drug even at lower doses. Reported two cases of akathisia, drug- induced Parkinsonism and one case of galactorrhea, amenorrhea.

 

Keywords: Galectorrhea; Amisulpride; Amenorrhea

References

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  2. Bressen RA., et al. “Is regionally selective D2/D3 dopamine occupancy sufficient for atypical antipsychotic effect? An In vivo quantitative epidepride SPET study of Amisulpride-treated patients”. The American Journal of Psychiatry 160 (2003): 1413-1420.
  3. Danion JM., et al. “Improvement of schizophrenic patients with primary negative symptoms treated with amisulpride. Amisulpride Study Group”. The American Journal of Psychiatry 156 (1999): 610-616.
  4. IaFougere C., et al. “D2 receptor occupancy during high and low-dose therapy with the atypical antipsychotic amisulpride: A123 I-iodobenzamide SPECT study”. Journal of Nuclear Medicine 46 (2005): 1028-1033.
  5. Leucht S., et al. “Amisulpride, an unusual “atypical” antipsychotic: A meta-analysis of randomized controlled trials”. The American Journal of Psychiatry 159 (2002): 180-190.
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Citation

Citation: Padmaraj B Patil. “Galactorrhea, Amenorrhea and Extrapyramidal Side Effects with Low Doses of Amisulpride". Acta Scientific Neurology 5.11 (2022): 15-17.

Copyright

Copyright: © 2022 Padmaraj B Patil. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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