Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Case Report Volume 5 Issue 11

Galactorrhea, Amenorrhea and Extrapyramidal Side Effects with Low Doses of Amisulprideg

Padmaraj B Patil

Consultant Psychiatrist Kamala Hospital, Kolhapur, Maharastra, India

*Corresponding Author: Padmaraj B Patil, Consultant Psychiatrist Kamala Hospital, Kolhapur, Maharastra, India.

Received: July 12, 2022; Published: October 07, 2022

Abstract

In India, amisulpride comparatively new antipsychotic which is claimed to be effective in both positive and negative symptoms schizophrenia and other disorder even though it has little or no action on serotonergic receptors. Lower striatal dopaminergic receptor binding capacity and limbic selectivity causes of EPS. But, in clinical practice, we are getting EPS with this drug even at lower doses. Reported two cases of akathisia, drug- induced Parkinsonism and one case of galactorrhea, amenorrhea.

 

Keywords: Galectorrhea; Amisulpride; Amenorrhea

References

  1. Boyer P., et al. “Amisulpride verses amineptine and placebo for the treatment of dysthymia”. Neuropsychobilogy 39 (1999): 25-32.
  2. Bressen RA., et al. “Is regionally selective D2/D3 dopamine occupancy sufficient for atypical antipsychotic effect? An In vivo quantitative epidepride SPET study of Amisulpride-treated patients”. The American Journal of Psychiatry 160 (2003): 1413-1420.
  3. Danion JM., et al. “Improvement of schizophrenic patients with primary negative symptoms treated with amisulpride. Amisulpride Study Group”. The American Journal of Psychiatry 156 (1999): 610-616.
  4. IaFougere C., et al. “D2 receptor occupancy during high and low-dose therapy with the atypical antipsychotic amisulpride: A123 I-iodobenzamide SPECT study”. Journal of Nuclear Medicine 46 (2005): 1028-1033.
  5. Leucht S., et al. “Amisulpride, an unusual “atypical” antipsychotic: A meta-analysis of randomized controlled trials”. The American Journal of Psychiatry 159 (2002): 180-190.
  6. Martinot JL., et al.In vivo characteristics of dopamine D2 receptor occupancy by amisulpride in schizophrenia”. Psychopharmacology (Beri) 124 (1996): 154-158.

Citation

Citation: Padmaraj B Patil. “Galactorrhea, Amenorrhea and Extrapyramidal Side Effects with Low Doses of Amisulpride". Acta Scientific Neurology 5.11 (2022): 15-17.

Copyright

Copyright: © 2022 Padmaraj B Patil. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate32%
Acceptance to publication20-30 days

Indexed In




News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is December 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"

Contact US