Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Case Report Volume 5 Issue 10

Expansile Sinonasal Ancient Schwanomma: A Rare Cause of Long-Standing Globe Displacement

MD Abdullah1, Kartik Manoj Multani1*, Kanakam Chandrakanth1, Boyina Jagadishwar Rajesh2 and Milap Shah3

1Resident, Department of neurosurgery, Yashoda Superspeciality hospital, Secunderabad, India
2Consultant, Department of Neurosurgery, Yashoda Hospital, Secunderabad, India
3Consultant and Head, Department of Pathology, Yashoda Hospital, Secunderabad, India

*Corresponding Author: Kartik Manoj Multani, Resident, Department of neurosurgery, Yashoda Superspeciality hospital, Secunderabad, India.

Received: November 18, 2021; Published: September 16, 2022


Ancient schwannomas are slow growing variant of benign schwannoma. Although commonly occur in head and neck region, the Sinonasal ancient schwannoma with extension into orbit are sparsely reported. Histopathologically, these tumours develop degenerative changes due to their long-standing nature and thus can be confused with malignant nerve sheath tumours or sarcoma. Diagnosis is made by combined HPE and Immunohistochemical analysis that reveals diffuse S-100 positive staining. Treatment of choice is surgical gross total excision. We present to the best of our knowledge, a fourth in world literature report of Sinonasal ancient schwannoma with intraorbital extension presenting to our OPD with abaxial displacement of involved globe and was treated with pure endoscopic gross total removal by transnasal route.

Keywords: Expansile; Sinonasal; Long-Standing; Globe Displacement


  1. Batsakis J. “Tumors of the head and neck: Clinical and pathological considerations”. Baltimore, MD: Wiley (1974): 231-249.
  2. SA Rasbridge NLB., et al. “Malignant nerve sheath tumour arising in a Benign Ancient Schwannoma”. Histopathology5 (1989): 525-528.
  3. Kodama S., et al. “Ancient schwannoma of the nasal septum associated with sphenoid sinus mucocele”. Auris, Nasus, Larynx4 (2010): 522-525.
  4. Hillstrom RP ZR and Jacobs JR. “Nerve sheath tumors of the paranasal sinuses: electron microscopy and histopathologic diagnosis”. Otolaryngol Head Neck Surgurey3 (1990): 257-263.
  5. Klijanienko JCJ and Lagace R. “Cytohistologic correlations in schwannomas (neurilemmomas), including ‘‘ancient,’’ cellular, and epithelioid variants”. Diagn Cytopathol (2006): 517-522.
  6. Patil SK Chatura and Kasimsetty Chatura. “Schwannoma and its unusual variants - A histopathological study”. Indian Journal of Pathology and Oncology 3 (2016): 727-731.
  7. Ackerman LV TF. “Neurogenous tumors within the thorax: A clinicopathological evaluation of forty-eight cases”. Cancer 4 (1951): 669-691.
  8. Shilpa B. “Ancient schwannoma-a rare case”. Ethiopian Journal of Health Sciences 3 (2012): 215-218.
  9. Gupta G., et al. “Malignant peripheral nerve sheath tumors”. Neurosurgery Clinics of North America4 (2008): 533-543.
  10. Miettinen M. “From morphological to molecular diagnosis of soft tissue tumors”. Advances in Experimental Medicine and Biology 587 (2006): 99-113.


Citation: Kartik Manoj Multani. “Expansile Sinonasal Ancient Schwanomma: A Rare Cause of Long-Standing Globe Displacement". Acta Scientific Neurology 5.10 (2022): 25-29.


Copyright: © 2022 Kartik Manoj Multani. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate32%
Acceptance to publication20-30 days

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is May 30, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US