Jin Tao1, Vibhav Bansal2*, Dorothy Bennett1, Ayaz Gen1, Samridh Gupta3, Samantha Aguilar3, Roy El Koussa1, Sarah Linder2, Vijayta Geeta Bansal-Kapuria1 and Drew Rust1
1Internal Medicine, MercyHealth, Rockford, IL, USA
2Neurology, MercyHealth, Rockford, IL, USA
3University of Chicago College of Medicine, Rockford, IL, USA
*Corresponding Author: Vibhav Bansal, Neurology, MercyHealth, Rockford, IL, USA.
Received: July 26,2022; Published: August 08, 2022
Wernicke’ encephalopathy is a rare but potentially reversible neurological disorder characterized by ophthalmoplegia, ataxia and confusion. Wernicke’s encephalopathy occurs as result of severe vitamin B1 (i.e., thiamine) deficiency. The most common etiology of Wernicke’s encephalopathy is malnutrition among alcoholics. Here, we report an unusual case of hyperemesis gravidarum induced Wernicke’s encephalopathy. A 25-year-old female, G2P1, with recent miscarriage at 20 weeks gestation and hyperemesis gravidarum presented with 1-month history of confusion, blurred vision, and progressive bilateral lower extremity weakness. The magnetic resonance imaging of brain revealed bilateral symmetrical hyperintensities in the thalami, mammillary bodies, and surrounding aqueduct of the midbrain suggesting Wernicke’s encephalopathy. Patient was subsequently managed with aggressive thiamine replacement therapy. Her symptoms gradually improved, and she was eventually discharged to an inpatient rehabilitation facility for long term physical therapy. Wernicke’s encephalopathy is a rare complication of hyperemesis gravidarum. This case highlights the importance of recognizing neurological changes due to thiamine deficiency during pregnancy. We would like to emphasize the importance of thiamine supplementation and monitoring in pregnant women with severe and prolonged vomiting history.
Keywords: Hyperemesis Gravidarum; Wernicke’s Encephalopathy; Thiamine Deficiency; Ataxia; Confusion; Ophthalmoplegia
Citation: Vibhav Bansal., et al. “Hyperemesis Gravidarum Induced Wernicke’s Encephalopathy". Acta Scientific Neurology 5.9 (2022): 11-14.
Copyright: © 2022 Vibhav Bansal., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.