Approach to Narcolepsy - A Rare but Potentially Treatable Sleep Disorder!
Lakshmi Priya and Ashalatha Radhakrishnan*
Comprehensive Centre for Sleep disorders, Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram,
Kerala, India
*Corresponding Author:Ashalatha Radhakrishnan, Comprehensive Centre for Sleep disorders, Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Received:
March 01, 2022; Published: March 25, 2022
Abstract
‘Narcolepsy’ comes from French narcolepsie, which was first used by French physician Jean-Baptiste Edouard Gelineau in 1880. This French word came from a combination of Greek narke, meaning stupor or numbness, and lepsis, meaning a seizure. The tetrad of narcolepsy symptoms proposed by Yoss., et al. in 1957 consists of excessive daytime somnolence, hypnogogic hallucinations, sleep paralysis and cataplexy [1]. Narcolepsy is a chronic neurologic condition due to dysregulation of sleep wake cycle, affecting 1 in 3000 individuals with a bimodal peak of incidence at 15 and 36 years of age [2]. However, there is a diagnostic delay inspite of early age of onset partly due to limited awareness of this entity among physicians and partly due to the associated comorbidity burden among patients with Narcolepsy [3].
Keywords: Narcolepsy; Cataplexy; Hypocretin; SOREMPs; MSLT
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