Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Case Report Volume 5 Issue 4

Degeneration of the Splenium of the Corpus Callosum in an Attention Deficit Hyperactivity Disorder (ADHD) Patient: A Case Report

Ali Al-Smair1, Bilal F Shanti2*, Zaynab I Shanti3, Osama Saadeh4, Mohamed I Shanti5, Ahmad Saadeh6, Ihsan F Shanti7, Ahmad AlAli8

1Radiologist, Medray International Radiology Center, Amman Jordan
2Founder, Omnia Pain Consultants, Pain Medicine, Phoenix AZ, USA
3Second Year Medical Student, Royal College of Surgeons Ireland, University of Medicine and Health Sciences, Dublin Ireland
4Northeastern Illinois University, Department of Public Health, Chicago, IL, USA
5First Year Medical Student, St George University Medical School, Granada
6Intern doctor, M.D. University of Jordan, Faculty of medicine, Amman Jordan
7The American Clinic for Interventional Pain and Spine, Amman Jordan
8Neuroradiologist, fellow of the Royal Medical Services, Department of Radiology, Jordanian Ministry of Health, Amman Jordan

*Corresponding Author:Bilal F Shanti, Founder, Omnia Pain Consultants, Pain Medicine, Phoenix AZ, USA.

Received: March 09, 2022; Published: March 25, 2022

Abstract

Attention Deficit Hyperactivity Disorder (ADHD) is a common clinical and neurobehavioral disorder that has a serious impact on the patient and his/her loved ones. Structural deformities associated with ADHD have been described, of which the corpus callosum is one of the most parts studied.
Deformities involving the splenium of corpus callosum have a robust association with ADHD. In this manuscript, we present a case of degeneration of a hypoplastic splenium of corpus callosum in an ADHD patient detected on MRI 2 years after initial detection of hypoplasia of corpus callosum.
To our knowledge, and after searching the published scientific data, this case may be the first case to report degeneration of a hypoplastic splenium of corpus callosum in an ADHD patient. It highlights a few important points: sample age matching in studies focusing on neuroanatomy of ADHD, it provides possible evidence that neuroanatomy can change with time in ADHD, and its association to worsening ADHD symptoms.

Keywords: ADHD; Degeneration; Splenium; Corpus Callosum; Case Report

References

  1. Greenhill LL., et al. American Academy of Child and Adolescent Psychiatry. “Practice parameter for the use of stimulant medications in the treatment of children, adolescents, and adults”. Journal of the American Academy of Child and Adolescent Psychiatry2 (2002): 26S-49S.
  2. Bird HR., et al. “Patterns of diagnostic comorbidity in a community sample of children aged 9 through 16 years”. Journal of the American Academy of Child and Adolescent Psychiatry2 (1993): 361-368.
  3. Wilens TE and Biederman J. “Alcohol, drugs, and attention-deficit/ hyperactivity disorder: a model for the study of addictions in youth”. Journal of psychopharmacology (Oxford, England)4 (2006): 580-588.
  4. Association AP. “Diagnostic and Statistical Manual of Mental Disorders: Fourth Edition Text Revision (DSM-IV-TR) 4th edition”. American Psychiatric Association; Washington, DC (2000).
  5. Barkley RA and Biederman J. “Toward a broader definition of the age-of-onset criterion for attention-deficit hyperactivity disorder”. Journal of the American Academy of Child and Adolescent Psychiatry9 (1997): 1204-1210.
  6. Ivanov I., et al. “Morphological abnormalities of the thalamus in youths with attention deficit hyperactivity disorder”. The American Journal of Psychiatry4 (2010): 397-408.
  7. Martinussen R., et al. “A meta-analysis of working memory impairments in children with attention-deficit/hyperactivity disorder”. Journal of the American Academy of Child and Adolescent Psychiatry 4 (2005): 377-384.
  8. Posner J., et al. “Attention-deficit hyperactivity disorder”. Lancet (London, England)395.10222 (2020): 450-462.
  9. Luders E., et al. “Decreased callosal thickness in attention-deficit/hyperactivity disorder”. Biological psychiatry65.1 (2009): 84-88. 
  10. Manor C., et al. “Magnetic Resonance Imaging Findings in Fetal Corpus Callosal Developmental Abnormalities: A Pictorial Essay”. Journal of pediatric neurosciences15.4 (2020): 352-357.
  11. Blaauw J and Meiners LC. “The splenium of the corpus callosum: embryology, anatomy, function, and imaging with pathophysiological hypothesis”. Neuroradiology62.5 (2020): 563-585.
  12. Al-Hashim AH., et al. “Corpus callosum abnormalities: neuroradiological and clinical correlations”. Developmental Medicine and Child Neurology 58.5 (2016): 475-484.
  13. Vieira de Melo BB., et al. “Systematic overview of neuroanatomical differences in ADHD: Definitive evidence”. Developmental Neuropsychology43.1 (2018): 52-68.
  14. Albajara Sáenz A., et al. “Structural and functional neuroimaging in attention-deficit/hyperactivity disorder”. Developmental Medicine and Child Neurology61.4 (2019): 399-405.
  15.  

Citation

Citation: Bilal F Shanti., et al. “Degeneration of the Splenium of the Corpus Callosum in an Attention Deficit Hyperactivity Disorder (ADHD) Patient: A Case Report". Acta Scientific Neurology 5.4 (2022): 07-10.

Copyright

Copyright: © 2022Bilal F Shanti., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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