Iznak AF*, Iznak EV, Damyanovich EV, Krylova ES, Kuleshov AA and Kaleda VG

Mental Health Research Centre, Moscow, Russian Federation

*Corresponding Author: Iznak AF, Professor, Head of Laboratory of Neurophysiology, Mental Health Research Centre, Moscow, Russian Federation.

Received: November 15, 2021; Published: December 31, 2021

Abstract

Personality disorders (PD) in adolescence are widespread. It creates problems of social adaptation of patients and represents significant risk factors for auto-aggressive behavior, including suicidal one. The neurobiological basis and EEG markers of PD in adolescence have not been adequately studied. The aim of the study was identification of EEG features and their correlations with clinical parameters in adolescent patients with borderline personality disorder (BPD) and narcissistic personality disorder (NPD), possibly mediating some aspects of their clinical traits.

28 BPD patients (301.83, by DSM-5) and 24 NPD patients (301.81, by DSM-5), as well as 24 healthy controls (HC) aged 16-25 years were enrolled in the study. Clinical scales HDRS-21 and HAM-A were used for quantitative assessment of patient’s conditions. Pre-treatment background EEG was recorded, and EEG spectral analysis was carried out in 8 narrow frequency sub-bands. Descriptive statistics and correlation analysis of the set of EEG and clinical data were performed.

EEG spectral parameters in BPD did not differ significantly from those of HC. NPD shows the EEG signs of more activated brain cortex than in both BPD and norm caused by decreased functional state of the anterior cortical regions. The structure of correlations between EEG parameters and clinical scores also differed between BPD and NPD.

The data obtained suggests that these features of the functional organization of the brain activity may contribute to the disturbance of the processes of regulation of emotions and control of behavior in adolescent patients with BPD and NPD, more pronounced in NPD.

Keywords: Adolescence; Borderline Personality Disorder; Narcissistic Personality Disorder; Depression; Quantitative Electroencephalography

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Citation

Citation: Iznak AF., et al. “EEG Features in Adolescent Patients with Borderline and Narcissistic Personality Disorder". Acta Scientific Neurology 5.1 (2022): 30-37.

Copyright

Copyright: © 2022 Iznak AF., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.