EEG Features in Adolescent Patients with Borderline and Narcissistic Personality Disorder
Iznak AF*, Iznak EV, Damyanovich EV, Krylova ES, Kuleshov AA and Kaleda VG
Mental Health Research Centre, Moscow, Russian Federation
*Corresponding Author: Iznak AF, Professor, Head of Laboratory of Neurophysiology, Mental Health Research Centre, Moscow, Russian Federation.
November 15, 2021; Published: December 31, 2021
Personality disorders (PD) in adolescence are widespread. It creates problems of social adaptation of patients and represents significant risk factors for auto-aggressive behavior, including suicidal one. The neurobiological basis and EEG markers of PD in adolescence have not been adequately studied. The aim of the study was identification of EEG features and their correlations with clinical parameters in adolescent patients with borderline personality disorder (BPD) and narcissistic personality disorder (NPD), possibly mediating some aspects of their clinical traits.
28 BPD patients (301.83, by DSM-5) and 24 NPD patients (301.81, by DSM-5), as well as 24 healthy controls (HC) aged 16-25 years were enrolled in the study. Clinical scales HDRS-21 and HAM-A were used for quantitative assessment of patient’s conditions. Pre-treatment background EEG was recorded, and EEG spectral analysis was carried out in 8 narrow frequency sub-bands. Descriptive statistics and correlation analysis of the set of EEG and clinical data were performed.
EEG spectral parameters in BPD did not differ significantly from those of HC. NPD shows the EEG signs of more activated brain cortex than in both BPD and norm caused by decreased functional state of the anterior cortical regions. The structure of correlations between EEG parameters and clinical scores also differed between BPD and NPD.
The data obtained suggests that these features of the functional organization of the brain activity may contribute to the disturbance of the processes of regulation of emotions and control of behavior in adolescent patients with BPD and NPD, more pronounced in NPD.
Keywords: Adolescence; Borderline Personality Disorder; Narcissistic Personality Disorder; Depression; Quantitative Electroencephalography
- Sharp C and Fonagy P. “Practitioner Review: Borderline personality disorder in adolescence - Recent conceptualization, intervention, and implications for clinical practice”. Journal of Child Psychology and Psychiatry and Allied Disciplines12 (2015): 1266-1288.
- Ha C., et al. “Psychiatric comorbidity in hospitalized adolescents with borderline personality disorder”. The Journal of Clinical Psychiatry 5 (2014): e457-464.
- Kaess M., et al. “Borderline personality disorder in adolescence”. Pediatrics 4 (2014): 782-793.
- Cain NM and Boussi A. “Narcissistic Personality Disorder”. In: Zeigler-Hill V., and Shackelford TK, eds. “Encyclopedia of Personality and Individual Differences”. Springer International Publishing. Pages (2020): 3088-3096.
- Soloff PH and Chiappetta L. “Subtyping borderline personality disorder by suicidal behavior”. Journal of Personality Disorders ;26.3 (2012): 468-480.
- Coleman, et al. “Narcissistic personality disorder and suicidal behavior in mood disorders”. Journal of Psychiatric Research 85.1 (2017): 24-28.
- Krylova ES., et al. “Non-suicidal self-injury and its relation to suicidal behavior in youth patients with personality disorders”. Suicidology 1 (2019): 48-57.
- Krylova ES., et al. “Auto-aggressive behavior in patients with narcissistic and borderline personality disorder in youth”. Psikhicheskoe zdorovie [Mental Health];12 (2020): 37-47.
- Brown RC and Plener PL. “Non-suicidal self-injury in adolescence”. Current Psychiatry Reports 3 (2017): 1-8.
- Colle L., et al. “Self-Harming and sense of agency in patients with borderline personality disorder”. Frontiers in Psychiatry 1 (2020): 1-11.
- Dawood S., et al. “Pathological narcissism and nonsuicidal self-injury”. Journal of Personality Disorders 1 (2018): 87-108.
- Links PS and Eynan R. “The relationship between personality disorders and axis I psychopathology: Deconstructing comorbidity”. Annual Review of Clinical Psychology 9 (2013): 529-554.
- Brunner R., et al. “Neurobiological findings in youth with borderline personality disorder”. Scandinavian Journal of Child and Adolescent Psychiatry and Psychology1 (2015): 22-30.
- Brunner R., et al. “Reduced prefrontal and orbitofrontal gray matter in female adolescents with borderline personality disorder: is it disorder specific?” Neuroimage1 (2010): 114-120.
- Schulze L., et al. “Gray matter abnormalities in patients with narcissistic personality disorder”. Journal of Psychiatric Research 10 (2013): 1363-1369.
- Pop-Jordanova N., et al. “Analysis of EEG Characteristics and Coherence in Patients Diagnosed as Borderline Personality”. Pril (Makedon Akad Nauk Umet Odd Med Nauki)3 (2019): 57-68.
- Russ MJ., et al. “EEG theta activity and pain insensitivity in self-injurious borderline patients”. Psychiatry Research3 (1999): 201-214.
- Lee SM., et al. “Electroencephalographic Correlates of Suicidal Ideation in the Theta Band”. Clinical EEG and Neuroscience5 (2017): 316-321.
- Knyazev GG. “EEG correlates of personality types”. Netherlands Journal of Psychology.1 (2006): 78-87.
- Smith EE., et al. “Assessing and conceptualizing frontal EEG asymmetry: An updated primer on recording, processing, analyzing, and interpreting frontal alpha asymmetry”. International Journal of Psychophysiology 111 (2017): 98-114.
- Beeney JE., et al. “EEG asymmetry in borderline personality disorder and depression following rejection”. Personality Disorders2 (2014): 178-185.
- Moshirian Farahi SM., et al. “Neuroticism and Frontal EEG Asymmetry Correlated with Dynamic Facial Emotional Processing in Adolescents”. Frontiers in Psychology 10 (2019): 175.
- Iznak EV., et al. “EEG Asymmetries in Depressive Female Adolescents with Different Kinds of Auto-Aggressive Behavior”. Psychiatry (Moscow)3 (2020): 14-21.
- Iznak AF., et al. “Differences of EEG Frequency and Spatial Parameters in Depressive Female Adolescents with Suicidal Attempts and Non-suicidal Self-injuries”. Clinical EEG and Neuroscience6 (2021): 406-413.
- First MB., et al. “Structured clinical interview for DSM-5 personality disorders (SCID-5-PD)”. Washington: American Psychiatric Association Publishing (2016).
- Hamilton M. “A rating scale for depression”. Journal of Neurology. Neurosurgery and Psychiatry 23 (1960): 56-62.
- Hamilton M. “The assessment of anxiety states by rating”. British Journal of Medical Psychology 32 (1959): 50-55.
- Mitrofanov AA. “Computer system for analysis and topographic mapping of the brain electrical activity with a neurometric EEG data bank (description and application)”. Moscow (2005): 63.
- Forbes CE., et al. “The role of executive function and the dorsolateral prefrontal cortex in the expression of neuroticism and conscientiousness”. Social Neuroscience 9 (2014): 139-151.
- Lang S., et al. “Cortical inhibition in alexithymic patients with borderline personality disorder”. Biological Psychology2 (2011): 227-232.