Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Case Report Volume 4 Issue 12

Post-Covid 19 Rhino-orbito-cerebral Mucormycosis in a Diabetic Patient: A Case Report

Fatma Dhieb1, Meriem Jrad1*, Nour Ben Ghorbel1, Meriem Boumediene1, Rym Lahiani2 and Ines Riahi2>

1Department of Radiology, Charles Nicolle Hospital, Tunis, Tunisia
2Department of Otolaryngology, Charles Nicolle Hospital, Tunis, Tunisia

*Corresponding Author: Meriem Jrad, Department of Radiology, Charles Nicolle Hospital, Tunis, Tunisia.

Received: October 02, 2021; Published: November 18, 2021


Only a few cases of co-infection of Covid 19 and mucormycosis have been reviewed in literature.

We are presenting a case of a 59 years old diabetic female patient who had a rhino-orbito-cerebral fungal infection one month after being diagnosed positive to Covid-19.

While she was infected by the virus the patient was treated ambulatory with broad spectrum antibiotic therapy and methylprednisolone.

One month after, the patient was admitted to hospital due to nasal obstruction with right purulent rhinorrhea, headache, unilateral right side facial pain, swelling of the right eye, and severe decreased visual acuity with no perception of light. The examination highlighted a right complete ophthalmoplegia with areflective mydriasis, chemosis and periorbital cellulitis. A necrosis of the right side of nasal was seen in nasal endoscopy. Sinusal evacuation and debridement surgery was done, and the patient was put on broad antibiotics in addition to IV liposomal Amphotericin B.

Mucormycosis is a severe infection and often a fatal infection. Our report shows that physicians should consider the potential of secondary invasive fungal infection in patient suffering with Covid-19.

Keywords: Mucormycosis; Covid19; Invasive Fungal Infection; CT Scan; MRI


  1. Chen I Wen and Cheng-Wei Lin. “Rhino-orbital-cerebral mucormycosis”. CMAJ: Canadian Medical Association Journal 16 (2019): E450.
  2. Jeong W., et al. “The Epidemiology and Clinical Manifestations of Mucormycosis: A Systematic Review and Meta-Analysis of Case Reports”. Clinical Microbiology and Infection1 (2019): 26‑34.
  3. Salil Mehta and Abha Pandey. “Rhino-Orbital Mucormycosis Associated With COVID-19”. Cureus 9 (2020).
  4. Mekonnen Zesemayat K., et al. “Acute Invasive Rhino-Orbital Mucormycosis in a Patient With COVID-19-Associated Acute Respiratory Distress Syndrome”. Ophthalmic Plastic and Reconstructive Surgery2 (2021): e40‑80.
  5. Garces P., et al. “Rhinocerebral Mucormycosis in a Child with Leukemia: CT and MRI Findings”. Pediatric Radiology 1 (1994): 50‑51.


Citation: Meriem Jrad., et al. “Post-Covid 19 Rhino-orbito-cerebral Mucormycosis in a Diabetic Patient: A Case Report”. Acta Scientific Neurology 4.12 (2021): 37-40.


Copyright: © 2021 Meriem Jrad.,et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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