Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Case Report Volume 4 Issue 12

Co-existence of Acute Transverse Myelitis and Guillain Barre Syndrome in a Child Following Mumps Infection: A Case Report and Review of Literature

Rajniti Prasad*, Pradhap K and Meenakshi Pandey

Division of Pediatric Neurology, Institute of Medical Sciences, B.H.U., Varanasi, India

*Corresponding Author: Rajniti Prasad, Professor and Chief, Division of Pediatric Neurology, Department of Pediatrics, Institute of Medical Sciences, B.H.U., Varanasi, India.

Received: August 16, 2021; Published: November 10, 2021

Abstract

The co-existence of Acute transverse myelitis (ATM) and Guillain-Barre syndrome (GBS) as a result of auto antibodies directed against self-neural antigens following mumps infection in children is rare. We present a 3-years boy admitted with weakness of both lower limbs with provisional diagnosis of transverse myelitis based on clinical and MRI findings. The patient was treated with intravenous methylprednisolone without significant recovery. The diagnosis was later revised to include GBS on the basis of CSF analysis and neurophysiological evidence of acute motor axonal neuropathy. A dual pathology of ATM and GBS may require intensive therapy directed against both diseases.

Keywords: Acute Transverse Myelitis; Guillain-Barre Syndrome; Mumps

References

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  3. Duncan S., et al. “Mumps and Guillain- Barre´ syndrome”. Journal of Neurology, Neurosurgery, and Psychiatry 53 (1990): 709.
  4. Venketasubramanian N. “Transverse myelitis following mumps in an adult - a case report with MRI correlation”. Acta Neurologica Scandinavica 96 (1997): 328-331.
  5. Howell KB., et al. “Concomitant transverse myelitis and acute motor axonal neuropathy in an adolescent”. Pediatric Neurology5 (2007): 378-381.
  6. Gupta AK., et al. “Coexisting Acute Transverse Myelitis and Guillain-Barré Syndrome in a Child: A Rare Presentation”. Journal of Pediatric Neurology4 (2016): 161-163.
  7. Bajaj NPS., et al. “Acute transverse myelitis and Guillain-Barre´ overlap syndrome with serological evidence for mumps viraemia”. Acta Neurologica Scandinavica 104 (2001): 239-242.

Citation

Citation: Rajniti Prasad., et al. “Co-existence of Acute Transverse Myelitis and Guillain Barre Syndrome in a Child Following Mumps Infection: A Case Report and Review of Literature”. Acta Scientific Neurology 4.12 (2021): 07-11.

Copyright

Copyright: © 2021 Rajniti Prasad., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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