Rasolonjatovo EC¹*, Rakotovao TK¹, Tsiaremby MG¹, Ramarokoto M¹, Ratovondrainy W², Rabarijaona M³ and Adriamamaomonjy C¹

¹Neurosurgery Department, Joseph Andrianavalona University Hospital Center (CHU-HJRA), Antananarivo, Madagascar
²Neurosurgery Department, Soavinadriana Hospital Center (CENHOSOA),Antananarivo, Madagascar
³Department of Neurosurgery, University Hospital Center (CHU) Tambohobe, Fianarantsoa, Madagascar

*Corresponding Author: Rasolonjatovo EC, Neurosurgery Department, Joseph Andrianavalona University Hospital Center (CHU-HJRA), Antananarivo, Madagascar.

Received: August 23, 2021; Published: September 23, 2021

Abstract

Introduction: NTDs are malformations of the central nervous system. It’s therapeutic complexities and the functional future of the child are the challenges in their management. The main objective of this study is to identify the epidemiological profile and short-term prognosis of these abnormalities.

Methods: This is a retrospective, descriptive study over a period of four years.

Results: The frequency of NTDs was of the order of 10 cases/year. The male gender was the most affected with a sex ratio of 2. The most common anatomoclinical form was Meningocele (53.65%). The association with congenital hydrocephalus found in this study was 26.82%. Nearly thirty-four percent of cases were children born of younger mothers, and the prenatal consultation rate was effective for 51.21%. Maternal infection was found in 58.53%. Folic acid intake during pregnancy was found in 82.73%. Surgery repair of the deformity was generally successful. Meningitis was the main complication. There were 4.87% of deaths related to serious cardiopulmonary diseases.

Conclusion: A clear male predominance of this condition, a significant history of maternal infection, the majority of anterior meningocele type topography, specify our series. Surgical outcomes are generally good except for a few manageable infected cases. The periconceptional and prenatal regular consultations are to be sensitized in order to prevent and reduce these abnormalities.

Keywords: Folic Acid; Prenatal Ultrasonography; Surgery; Tube Neural Defects

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Citation

Citation: Rasolonjatovo EC., et al. “Neural Tube Malformations: Monocentric Results of Operated Cases”. Acta Scientific Neurology 4.10 (2021): 38-44.

Copyright

Copyright: © 2021 Rasolonjatovo EC., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.