Ganesh Sonawane¹, Biju S Pillai² and H Krishna Moorthy²*

¹Senior Resident, Division of Urology, Lourdes Institute of Nephro-Urology, Lourdes Hospital, Kochi, India
²Consultant Urologists, Division of Urology, Lourdes Institute of Nephro-Urology, Lourdes Hospital, Kochi, India

*Corresponding Author: H Krishna Moorthy, Consultant Urologists, Division of Urology, Lourdes Institute of Nephro-Urology, Lourdes Hospital, Kochi, India.

Received: July 25, 2021; Published: August 30, 2021

Abstract

Introduction: Transurethral resection of prostate (TURP) is the mainstay of surgery for Benign Prostatic Hyperplasia (BPH). However it is estimated that upto 20% of patients have unfavourable results after TURP, suggesting certain other factors affecting outcome of TURP. Neurological changes occurring in the urinary bladder in patients with long standing BPH have been widely postulated as the reason for this poor outcome in some patients. This study was undertaken to assess the role of various intrinsic factors other than neurological causes, influencing outcome of TURP for BPH.

Materials and Methods: This was a prospective study on 120 cases of BPH qualifying inclusion criteria with absolute indications for TURP. Detailed physical, sonological and biochemical evaluation were done pre and post (1 and 3 months) TURP. The results of surgery were compared in various groups to evaluate the role of intrinsic factors like age of patients, prostate size, UTI, catheterization status, grades of diverticula, presence of diverticula and post void residue (PVR) in the outcome of TURP.

Results: There was significant difference in symptom score and flow patterns in pre and post operative patients classified into different groups according to the age, presence of UTI and PVR volume. The post operative flow rates were significantly lower in grade III trabeculation patients compared to other groups. The post operative symptom score was significantly lower and flow rates were higher in the group without diverticula.

Conclusions: Elderly patients (>65years) and patients without UTI before TURP had better functional outcome after TURP. Larger glands (>45grams) had favourable outcome, while poorer outcome was found in patients with higher grades of bladder trabeculations. However, there was no difference in outcome between catheterised and non-catheterised patients. Therefore there is significant role of non-neurological factors in the outcome of TURP for BPH.

Keywords: Benign Prostatic Hyperplasia; Trans Urethral Resection of Prostate; Urodynamics; International Prostate Symptom Score

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Citation

Citation: H Krishna Moorthy., et al.“Can Non-neurological Intrinsic Factors Affect Outcome of TURP in Patients with BPH?". Acta Scientific Neurology 4.9 (2021): 77-85.

Copyright

Copyright: © 2021 H Krishna Moorthy., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.