Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Letter to Editor Volume 4 Issue 9

Hypothalamus and Hypothalamic Dysfunction in COVID-19

Luis Rafael Moscote-Salazar1, Md Moshiur Rahman2*, Sabrina Rahman3, Ivan David Lozada-Martinez4 and Mohammed Maan Al-Salihi5

1Center for Biomedical Research (CIB), Faculty of Medicine, University of Cartagena, Cartagena, Colombia
2Assistant Professor, Neurosurgery Department, Holy Family Red Crescent Medical College, Dhaka, Bangladesh
3Department of Public Health, Independent University-Bangladesh, Dhaka, Bangladesh
4Medical and Surgical Research Center, School of Medicine, University of Cartagena, Cartagena, Colombia
5Medical Doctor, College of Medicine, University of Baghdad, Baghdad, Iraq

*Corresponding Author: Md Moshiur Rahman, Assistant Professor, Neurosurgery Department, Holy Family Red Crescent Medical College, Dhaka, Bangladesh.

Received: August 12, 2021; Published: August 28, 2021

  The recent pandemic associated with the new coronavirus has represented a new paradigm in different aspects of medicine [1]. The neuroinvasive properties verified regarding SARS-Cov2 have allowed us to know how this virus affects multiple organs and systems in the human body [2,3]. One of the affected structures is the hypothalamus, an anatomical region located in the diencephalon with different vital functions for the body's normal functioning [4,8].


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  3. Traore A., et al. “Neurologie et COVID-19”. Revue Médicale Suisse 692 (2020): 947-949.
  4. Fukushi I., et al. “The role of the hypothalamus in modulation of respiration”. Respiratory Physiology and Neurobiology 265 (2019): 172-179.
  5. Vikhert AM., et al. “Osobennosti gipotalamusa pri vnezapnoĭ serdechnoĭ smerti cheloveka [Hypothalamic characteristics in sudden human cardiac death”. Kardiologiia 7 (1980): 75-80.
  6. Martin A Samuels. “Neurogenic heart disease: A unifying hypothesis”. The American Journal of Cardiology18 (1987): J15-J19.
  7. Beri A and Kotak K. “Cardiac injury, arrhythmia, and sudden death in a COVID-19 patient”. Heart Rhythm Case Report7 (2020): 367-369.
  8. Pal R. “COVID-19, hypothalamo-pituitary-adrenal axis and clinical implications”. Endocrine 2 (2020): 251-252.
  9. Nampoothiri S., et al. “The hypothalamus as a hub for SARS-CoV-2 brain infection and pathogenesis”. bioRxiv (2020).
  10. Poyiadji N., et al. “COVID-19-associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features”. Radiology (2020): 201187.
  11. Jenkins JS. “The hypothalamus”. British Medical Journal 2 (1972): 99-102.


Citation: Md Moshiur Rahman., et al. “Hypothalamus and Hypothalamic Dysfunction in COVID-19”. Acta Scientific Neurology 4.9 (2021): 54-55.


Copyright: © 2021 Md Moshiur Rahman., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate32%
Acceptance to publication20-30 days

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