Covid-19 Infection and Meningoencephalitis in Pregnancy: A Case at the Douala Gynaeco-obstetric and Pediatric Hospital of Douala

Djomo Tamchom Dominique^1,5, Gueumekane Bila Lamou Eric^1,3*, Onana Yannick^1,2, Kamdem Modjo Diane Estelle¹, Habiba Noura Ben Moussa¹, Ngaba Guy Pascal^1,3 and Mboudou Emile Telesphore^1,3,4

¹Douala Gynaeco-Obstetric and Pediatric Hospital, Cameroon
²Faculty of Medicine and Biomedical Sciences, University of Ngaoundéré, Cameroon
³Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Cameroon
⁴Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon
⁵Faculty of Medicine, Free University of Brussels, Cameroon
⁶Faculty of Health Sciences, University of Buea, Cameroon

*Corresponding Author: Gueumekane Bila Lamou Eric, Douala Gynaeco-Obstetric and Pediatric Hospital, Cameroon.

Received: June 25, 2021; Published: August 07, 2021

Abstract

A 25-year-old expecting patient, G4P3 003, with no known pathological history, was referred to us for status epilepticus progressing for 2 days, on a pregnancy of 34 weeks of amenorrhea + 5 days, in a context of unspecified fever, without an increase in blood pressure (BP = 104/63 mmHg). The physical examination shows stiff meninges and post-critical coma with an estimated Glasgow score of 8/15 modified by aphasia, and vaginal examination is normal.

The biological assessment made on admission shows a normal blood count, ketonuria at 150 mg (+++) without proteinuria on the urine test strip. D-dimers, LDH and procalcitonin are high. An emergency obstetric ultrasound and brain CT scan are normal. Real-time PCR on a nasopharyngeal swab for COVID-19, routinely performed on admission in the context of a pandemic, revealed the presence of SARS-COV-2 RNA. The diagnostic hypotheses put forward were non-typical eclampsia, cerebral thrombophlebitis or meningoencephalitis in an active pregnancy associated with the COVID-19 disease. The management consisted of an emergency cesarean, a treatment protocol for COVID-19, an anticonvulsant and physiotherapy. The clinical progression was very satisfactory after 7 days. It is important to draw the attention of practitioners to the polymorphism of COVID-19 in vulnerable areas such as that of pregnant women.

Keywords: COVID-19; Meningoencephalitis; Pregnancy

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Citation

Citation: Gueumekane Bila Lamou Eric., et al. “Covid-19 Infection and Meningoencephalitis in Pregnancy: A Case at the Douala Gynaeco-obstetric and Pediatric Hospital of Douala”. Acta Scientific Neurology 4.9 (2021): 12-17.

Copyright

p id="fulltextheader1" style="padding:3px;">Copyright: © 2021 Gueumekane Bila Lamou Eric., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.