Vinod Kumar Tewari1*, Neeraj Seth2, Devesh Johari3 and Lori Tewari4
1Neurosurgeon, Director, Advance Neuro and General Hospital, Lucknow, India
2Physiotherapist, Advance Neuro and General Hospital, Lucknow, India
3Opthalmologist, Jodhpur, Rajasthan, India
4Advance Neuro and General Hospital, Lucknow, India
*Corresponding Author: Vinod Kumar Tewari, Neurosurgeon, Director, Advance Neuro and General Hospital, Lucknow, India.
Received: October 09, 2020; Published: December 14, 2020
Leg muscle cramps in cervical myelopathic changes is inconsistent symptom and later on very disturbing to the patient specially in night time while taking rest. NO is generated by nitric oxide synthase (NOS) which acts via 10000-fold effect to reverse the neuronal damage. We have used intrathecal sodium nitroprusside to activate the 10000-fold effect to modulate the retrograde neuroregulation in muscle cramps in cervical myelopathy in a case.
Keywords: Night Muscle Cramps; 10000-fold Effect; Intrathecal Sodium Nitroprusside
Citation: Vinod Kumar Tewari., et al. “Role of 10000-fold Effect in Improving Leg Cramps in Myelopathic Spinal Cord Changes – A Case Study". Acta Scientific Neurology 4.1 (2021): 15-17.
Copyright: © 2021 Vinod Kumar Tewari., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.