Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Research Article Volume 4 Issue 2

Sleep Disturbances and Association of Polymorphism rs2278749 Gene ARNTL in Male Population 25 - 44 Years in Russia/Siberia

Valery Gafarov1,2*, Elena Gromova1,2, Dmitriy Panov1,2, Igor Gagulin1,2, Almira Gafarova1,2 and Eldar Krymov1,2

1Collaborative Laboratory of Cardiovascular Diseases Epidemiology, Novosibirsk, Russia
2Institute of Internal and Preventive Medicine - Branch of Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

*Corresponding Author: Valery Gafarov, Doctor of Sciences (Medicine), Professor, Head of Laboratory of Psychological and Sociological Issues of Internal Diseases, Institute of Internal and Preventive Medicine - Branch of Institute of Cytology and Genetics SB RAS, Head Collaborative laboratory of Cardiovascular Diseases Epidemiology, Novosibirsk, Russia.

Received: October 23, 2020; Published: November 18, 2020

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Abstract

  It was found that the most common genotype rs2278749 ARNTL gene was homozygous C/C genotype - 74,9%. Prevalence of C/T and T/T genotype was 22.3% and 2.8%, respectively. It was revealed that persons with the genotype C/T more likely to experience serious conflicts in the family, more experienced their frustration, they often have disturbing dreams, and they wake up tired and exhausted, in addition, they often met the high level of the life of exhaustion, and they soon became frustrated. Persons with genotype T/T often took the trouble "to heart" and were more punctual. On the other hand, persons with C/C genotype were more hostile, were inclined not to trust anyone, almost "never" accept negative situations "close to the heart" and much less experienced disturbing dreams.

Keywords: The ARNTL Gene; Genetic Polymorphism; rs2278749; Sleep Disorders; Psychosocial Factors

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Citation

Citation: Valery Gafarov., et al. “Sleep Disturbances and Association of Polymorphism rs2278749 Gene ARNTL in Male Population 25 - 44 Years in Russia/Siberia". Acta Scientific Neurology 4.2 (2021): 02-08.




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