Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Case Report Volume 3 Issue 5

Enhancement of Function of the Prefrontal Cortex to Improve Symptoms of Schizophrenia

Prajjita Sarma Bardoloi*

Psychiatrist, Queen Elizabeth Hospital II, Grande Prairie, Alberta, Canada

*Corresponding Author: Prajjita Sarma Bardoloi, Psychiatrist, Queen Elizabeth Hospital II, Grande Prairie, Alberta, Canada.

Received: April 01, 2020; Published: April 28, 2020

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Abstract

 Schizophrenia is a chronic psychotic illness with multifactorial etiology that manifests with a constellation of positive, negative, affective and cognitive symptoms [1]. As we are learning more about the neurobiology of schizophrenia, the role of the prefrontal cortex (PFC) in schizophrenia has become more evident. While various medications are available to treat psychotic symptoms in schizophrenia, treatment of cognitive functions, residual symptoms and comorbid disorders is still a substantial challenge. Here we present a case of a young male who suffers from schizophrenia, with a previous diagnosis of ADHD and substance abuse, who showed remarkable improvement following treatment with the alpha-2A adrenergic agonist guanfacine, likely related to enhanced PFC function.

Keywords: Schizophrenia; Prefrontal Cortex (PFC); Dopaminergic (DA)

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Citation

Citation: Prajjita Sarma Bardoloi. “Enhancement of Function of the Prefrontal Cortex to Improve Symptoms of Schizophrenia".Acta Scientific Neurology 3.5 (2020): 19-23.




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Acceptance rate32%
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Impact Factor0.844

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