Eric Gueumekane Bila Lamou1*, Adjaratou Dieynabou Sow1, Anna Modji Basse Faye1, Yacouba Njankouo Mapoure2, Soumaila Boubacar1, Ngor Side Diagne1, Kamadore Toure1, Moustapha Ndiaye1, Amadou Gallo Diop1 and Mouhamadou Mansour Ndiaye1
1Neurological Clinic, Fann Teaching Hospital, Dakar, Fann, Senegal
2Douala General Hospital, Cameroon
*Corresponding Author: Eric Gueumekane Bila Lamou, Neurological Clinic, Fann Teaching Hospital, Dakar, Fann, Senegal.
Received: February 28, 2020 March 17, 2020; Published: March 30, 2020
Introduction: The Cortical malformations are one of important causes of epilepsy, mental retardation and other neurological disorders. The Schizencephaly is an abnormality of the cortical organization characterized by cracks connecting the pial’s surface to the lateral ventricle. Considered as a sporadic anomaly, its genetic origin is likely, involving an EMX2 gene mutation. The clinic depends on the size and location of the slot, and the age of diagnosis.
Patients and Methods: We report clinical observations of a 32-year old woman and a man of 41 years. The Clinical presentation was totally different but they had a single common denominator as seizures with variable onset and type, which were the origin of diagnosis. Their evolution had been variable with drug resistance in one case and a neurosurgical derivation for tetraventricular hydrocephalus.
Discussion and Conclusion: Schizencephaly is a source of earlier onset often focal seizures. Late onset in our case denotes of a certain brain adaptation. Imagery is paramount in the positive diagnosis and the lesional checking.
Keywords: Schizencephaly; Epilepsy; Drug Resistance; Dakar; Senegal
Citation: Eric Gueumekane Bila Lamou., et al “Epilepsy and Cortical Malformation Type Schizencephaly: Concerning Two Cases Revealed in Young Adult"Acta Scientific Neurology 3.4 (2020): 44-49.
Copyright: © 2020 Eric Gueumekane Bila Lamou., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.