Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Mini Review Volume 3 Issue 3

Adult Craniopharyngioma Management: What’s the Next Step?

Sameh Elmorsy Hassan Elmorsy*

El-Matrya Educational Hospita, Cairo University, Egypt

*Corresponding Author: Sameh Elmorsy Hassan Elmorsy, El-Matrya Educational Hospita, Cairo University, Egypt.

Received: January 26, 2020; Published: February 26, 2020

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Abstract

  A lot of troubles we are facing as neurological surgeons when we deal with this tumor. Although it’s a benign tumor histologically, it has a malignant cellular characteristic, causes a big trouble in surgery and postsurgical treatment. It is divided into two types: adamantinomatous and papillary craniopharyngioma. The first surgical techniques for craniopharyngioma originated in 1891 by Selke. There is consensus that best management is surgery but there is trend developed recently between surgeons which is that subtotal resection is better to maintain function of surrounding structures, also total removal of this tumor surgically is challenging because of tight adherence of its capsule to lot of very important structures, In Best surgical hands this tumor is not favorable for resection because of multiple functional complications intraoperative and postoperative. Endocrine abnormalities are commonly seen postoperatively in the form of hypopituitarism. Immunotherapy including EGFR inhibitors such gefitinib, erlotinib, and lapatinib are now off-label use in treatment of craniopharyngiomas. In 2019 Rao., et al. reported treated case with selective BRAF inhibitor dabrafenib. Till now we didn’t reach the ideal management for this benign tumor although surgery is the best. we need to take a different step in the direction of searching for better management of this tumor.

Aim and Type: This is short review to search in literature about ideal management for adult craniopharyngioma and what is the next step that we should talk to get better outcome.

Methodology: Different online medical databases have been reviewed to search for best management of this tumor including PubMed and Cochrane and authors surgical team experience 

Conclusion: We need more studied in the future either surgically or immunologically to face this benign tumor to get less complications preoperative and postoperative to improve patients’ outcome. we need to know what’s is the next step of management.

Keywords: Craniopharyngioma; Adamantinomatous; Papillary Craniopharyngioma

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References

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Citation

Citation: Sameh Elmorsy Hassan Elmorsy. “Adult Craniopharyngioma Management: What’s the Next Step?”. Acta Scientific Neurology 3.3 (2020): 09-11.




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Acceptance rate32%
Acceptance to publication20-30 days
Impact Factor0.844

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