Acta Scientific Clinical Case Reports

Case Report Volume 2 Issue 7

Nephrogenic Cholestatic Jaundice

Tara Kannan1 and Adel Ekladious2*

1Medical Student, School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia
2Internal Medicine Specialist, Faculty of Health and Medical Sciences, University of Western Australia, Perth, WA, Australia

*Corresponding Author: Adel Ekladious, Internal Medicine Specialist, Faculty of Health and Medical Sciences, University of Western Australia, Perth, WA, Australia.

Received: April 20, 2021; Published: June 16, 2021


Cholestasis due to liver metastasis is more common than primary liver carcinoma.

Common cancers that metastasize to the liver are colorectal cancer followed by breast and pancreas, to the best of our knowledge very few malignancies can cause paraneoplastic cholestasis which are renal cell carcinoma followed by lymphoproliferative disease and cancer prostate.

Stauffer syndrome is a paraneoplastic cholestasis due to renal cell carcinoma, commonly cause fever and cholestatic liver function in the absence of any metastatic involvement, treating renal cell carcinoma usually cures liver cholestasis.

We present a patient with fever and advanced renal cell carcinoma in the absence of liver involvement.

Due to end stage renal carcinoma another comorbidity, patient and family opt to palliative management.

Keywords: Cholestasis; Liver Carcinoma; Lymphoproliferative Disease; Cancer Prostate


  1. Fontes-Sousa Mário., et al. “Stauffer’s syndrome: a comprehensive review and proposed updated diagnostic criteria”. Urologic Oncology: Seminars and Original Investigations7 (2018).
  2. Kranidiotis Georgios P.., et al. “Stauffer's syndrome as a prominent manifestation of renal cancer: a case report”. Cases Journal1 (2009): 1-4.
  3. Sharma Neha., et al. “Stauffer syndrome: a comprehensive review of the icteric variant of the syndrome”. Cureus10 (2019).


Citation: Tara Kannan and Adel Ekladious. “Nephrogenic Cholestatic Jaundice". Acta Scientific Medical Sciences 5.7 (2021): 44-52.


Copyright: © 2021 Tara Kannan and Adel Ekladious. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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