Todd P Silverstein*

3800 West 57th Terrace, Fairway, KS 66205, USA

*Corresponding Author: Todd P Silverstein, Chemistry Department (Emeritus), Willamette University, Salem, OR 97301, USA.

Received: August 31, 2026; Published: October 14, 2026

Abstract

In a recent Landmark Review (Amer. J. Physiol.-Cell Physiol. (2025) 329: C1944-1984), James Lee described his body of published work employing the transmembrane-electrostatically localized protons/cations charges (TELPs/TELCs) hypothesis. In addition to enumerating the usefulness of his model in explaining basic biological processes like oxidative phosphorylation and neurotransmission, and in re-interpreting experimental results reported by others, Lee strove to express and support his conclusion that “the putative potential well/barrier model is not needed to explain… protonic bioenergetics”. In this paper I critique this unwarranted conclusion, and also enumerate other serious problems with the equations, calculations, conclusions, and presentation of the scientific literature found in Lee’s Landmark Review.

Keywords: Capacitor; Protons

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Citation

Citation: Todd P Silverstein. “Protonic Capacitor Cell Energetics: Serious Problems to Consider". Acta Scientific Microbiology 9.10 (2026): 31-57.

Copyright

Copyright: © 2026 Todd P Silverstein. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.