Parijat N Goswami¹*, Nidhi H Barot² and Mitali R Maradia³

¹Professor and Head, Department of Microbiology, Sal Institute of Medical Sciences, Ahmedabad, India
²Senior Resident, Department of Microbiology, Sal Institute of Medical Sciences, Ahmedabad, India
³Associate Professor, Department of Microbiology, Sal Institute of Medical Sciences, Ahmedabad, India

*Corresponding Author: Parijat N Goswami, Professor and Head, Department of Microbiology, Sal Institute of Medical Sciences, Ahmedabad, India.

Received: June 05, 2025; Published: June 09, 2025

Abstract

Background: Urinary tract infections (UTIs) are caused by microorganism invading and inducing inflammatory response of the urinary tract presenting with signs and symptoms. UTIs are among the most common infections worldwide and the second most common cause of sepsis. The aim of the present retrospective study is to know the common pathogen isolated from the urine culture and sensitivity of the admitted patients, antibiogram preparation and create antibiotic policy.

Material and Method: This study was carried out in the NABL accredited Microbiology department of SAL Hospital and Medical institute, Ahmedabad, Gujarat for a period of one year from January to December 2024. All standard techniques for culture, identification and antibiotic susceptibility testing (AST) were performed according to CLSI guideline 2024 [3]. The data was analyzed through WHONET as well as MS Excel.

Result: A total of 356 urine samples were received from different areas like ICU, ward and OPD of the hospital in one year duration. Out of 356 urine samples, 115 samples were culture positive with significant bacterial growth. Urinary tract infections including catheterized patients was 32.3% on the whole out of the total samples received (115/356) in 2024. Out of the total samples of 356 urine samples, 48 (13.48%) samples were from the catheterized patients. The common uro pathogens were E. coli (40.86%), and Pseudomonas sp. (30.43%). Maximum E. coli (84%) were sensitive to nitrofurantoin followed by Gentamicin (68%), Meropenem (56%), Amp-sulbactum (43%). Klebsiellas species was found to be multi drug resistant (MDR). Pseudomonas (n = 35) were sensitive to most of the antibiotics (50-58%).

Conclusion: Due to increasing antibiotic resistance causing UTIs, it is a commitment of the microbiologists to actively prepare antibiogram and contribute for Antimicrobial stewardship programme.

Keywords: Urinary Tract Infection (UTIs); Antibiogram; Antibiotic Policy

References

1. Flores-Mireles AL., et al. “Urinary tract infections: epidemiology, mechanisms of infection and treatment options”. Nature Reviews Microbiology5 (2015): 269-284.
2. Singh A., et al. “The study of antibiotic-sensitivity and resistance pattern of bacteria causing catheter associated urinary tract infection”. International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9 (2020): 3196.
3. “Clinical and Laboratory Standard Institute (CLSI) guidelines”. (2024).
4. Pardeshi P. “Prevalence of urinary tract infections and current scenario of antibiotic susceptibility pattern of bacteria causing UTI”. Indian Journal of Microbiology Research3 (2024): 334-338.

Citation

Citation: Parijat N Goswami., et al. “Retrospective Study of Urinary Tract Infection in Patients Admitted in a Teaching Hospital of Medical College".Acta Scientific Microbiology 8.7 (2025): 02-06.

Copyright

Copyright: © 2025 Parijat N Goswami., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.