Monsi Tombari Pius¹*, Ekwusa Vivian Obiageri¹, Adebayo Olugbenga Adegoke² and Chinwebudu Miller Melford³*

¹Department of Medical Microbiology, Faculty of Medical Laboratory Science, Rivers State University, Nkpolu-Oroworukwo, Port Harcourt, Rivers State, Nigeria ²Department of Chemical Pathology, Madonna University, Rivers State, Nigeria ³Department of Medical Technology, College of Allied Medical Sciences, Cebu Doctors’ University, Mandaue City, Cebu, Philippines

*Corresponding Author: Monsi Tombari Pius, Department of Medical Microbiology, Faculty of Medical Laboratory Science, Rivers State University, Nkpolu-Oroworukwo, Port Harcourt, Rivers State, Nigeria.

Received: December 02, 2024; Published: January 13, 2025

Abstract

The study investigated the antibiogram profile of bacteria isolated from wounds of patients attending university of Port Harcourt Teaching Hospital, Port Harcourt. A total of 236 wound swab samples collected from road traffic accident (RTA) (56), diabetic foot ulcer (40), post-surgical wound (38), burns (20), chronic leg ulcer (CLU) (20) and soft tissue infections (62) from both the in and out-patients departments. These samples were processed, cultured and microbial isolates identified following standard operating protocols in a diagnostic microbiology laboratory. The samples with bacterial growth were 208 (88%) of which 28 (12%) was poly microbial growth. The most common pathogen isolated was Staphylococcus aureus 64 (27%) followed by P. aeruginosa 42 (18%), Klebsiella pneumoniae 36 (15%), Proteus sp., 24 (10%), Escherichia coli 20 (8%), Streptococcus pyogenes 6 (3%) while 16 (7%) had mixed growth and 28 (12%) had no bacterial growth. Overall, 132 (56%) female subjects and 104 (44%) male subjects had bacterial growth. Soft tissue wounds 68(28.81%) was the most infected wound followed by surgical wound infection 56 (24%), diabetic foot ulcer 46 (19%), burns 22 (9%), CLU 22 (9%) and RTA 22 (9%). Sensitivity of ofloxacin to S. aureus, Pseudomonas aeruginosa, Klebsiella sp., Proteus sp., E. coli and S. pyogenes was 60 (94%), 40 (95%), 30 (83%), 22 (92%), 20 (100%) and 5 (83%) while ciprofloxacin was 60 (94%), 40 (95%), 36 (100 %), 24 (100%), 20 (100%) and 5 (83%) respectively. Pefloxacin sensitivity was 62 (97%), 42 (100%), 36 (100%), 24 (100%), 20 (100%) and 5 (83%) to S. aureus, P. aeruginosa, Klebsiella sp., Proteus sp., E. coli and S. pyogenes respectively. This study showed S. aureus and P. aeruginosa are the top pathogen isolated from wound infections.

Keywords:Antimicrobial Resistance; Pathogens; Antibiotics; Epidemiology

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Citation

Citation: Monsi Tombari Pius., et al. “Prevalence and Antibiogram of Bacterial Pathogens Associated with Wounds in Patients Attending University of Harcourt Teaching Hospital". Acta Scientific Pharmaceutical Sciences 8.2 (2025): 23-34.

Copyright

Copyright: © 2025 Monsi Tombari Pius., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.