Acta Scientific Microbiology

Research Article Volume 8 Issue 2

Evaluation of Hepatitis B Vaccination Coverage of Patients Seen at the Abéché University Hospital, Chad

HI Nourdja1*, A Boiro2, TAL Balde2, A Youssouf1, MB Bah2, AA Yakhoub1, TD Camara5, LII Soumah2, S Boumbaly2, AA Doutoum3, ZA Zakaria3, A Hemici4 and MY Boiro2

1University Hospital Center of Abéché-Chad, BP: 87, Chad
2Institute of Applied Biology Research of Guinea (IRBAG/Kindia), BP: 146, Guinea
3Adam Barka University, Abéché, BP: 1173, Chad
4University May 8, 1945 of Guelma – Algeria, BP: 401, Algeria
5University Gamal Abdel Nasser of Conakry, BP: 1147, Guinea

*Corresponding Author: HI Nourdja, University Hospital Center of Abéché-Chad, BP: 87, Chad.

Received: November 11, 2024; Published: December 12, 2024

Abstract

Introduction: Hepatitis B is a viral infection caused by the hepatitis B virus, which leads to inflammation of the liver. Infection with the hepatitis B virus (HBV) is a major public health problem, with more than 250 million chronically infected people worldwide at high risk of cirrhosis and hepato cellular carcinoma.

Objective: To contribute to a better understanding of vaccination coverage against the hepatitis B virus at the University Hospital of Abéché, Chad.

Material and Methods: This prospective analytical study was carried out on a population of 808 consenting patients aged between 14 and 60 years, from 1 April to 31 December 2023, using the enzyme-linked immunosorbent assay (ELISA) to determine antibodies to the hepatitis B virus surface antigen.

Results: Before our study, we found 3 cases (0.37%), including 2 (0.25%) males and 1 (0.12%) female, in a population of 808 samples. After our study, 44 vaccinated cases were identified with a vaccination rate of (5.44%), including 25 (3.09%) males and 19 (2.35%) females.

Conclusion: We note that ignorance of the hepatitis B virus and its transmission routes are factors that favourits spread in Abéché. This could be explained by the low rate of people vaccinated, with 3 cases (0.37%) before the study, after awareness-raising, vaccination coverage increased to 5.44% (44 cases vaccinated).

Keywords:Vaccination Coverage; HBV; ELISA; Ouaddaï; Chad

References

  1. World Health Organization, Hepatitis B (2024).
  2. Demba SACKO. Connaissances, Attitudes et Pratiques des Consultants a Propos de l'hépatite Virale B Au Centre de Sante de Référence de La Commune IV du District de Bamako, Thèse Doctorat d'Etat 09/04/(2015): 84.
  3. Fanou Denis., et al. “Evaluation de l'état vaccinal contre l'hépatite B et portage de l'Ag HBs chez les militaires Béninois en mission en Côte d'Ivoire”. Pan African Medical Journal (2019).
  4. F Denis., et al. “Évolution des stratégies vaccales et couverture vaccinale contre l'hépatite B en France, pays de faible endémie” (2004).
  5. MJ Lohouès-Kouacou. “Knowledge and vaccination coverage against viral hepatitis B (HVB): cross-sectional study among students at the University of Cocody, Côte d'Ivoire Hepatitis B”.
  6. Assi C., et al. “Vaccination coverage against viral hepatitis B and prevalence of HBs antigen in a high-risk profession: a cross-sectional study of 244 firefighters in the city of Abidjan”. Clinics and Research in Hepatology and Gastroenterology 5 (2011): 115-118.
  7. C Njuguna., et al. “Introduction of hepatitis B vaccine at birth in Africa” (2022).
  8. Nanelin Guingane. Prévention de la transmission mère-enfant du virus de l'hépatite B au Burkina Faso : état des lieux et nouvelles stratégies, PhD thesis (2022): 120.

Citation

Citation: HI Nourdja., et al.“Evaluation of Hepatitis B Vaccination Coverage of Patients Seen at the Abéché University Hospital, Chad". Acta Scientific Microbiology 8.1 (2025): 41-46.

Copyright

Copyright: © 2025 HI Nourdja., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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