Acta Scientific Microbiology

Research Article Volume 7 Issue 3

Antibacterial Efficacy of Azardirachta indica (Neem) Against Oral Microorganisms- An In-vitro Study

Revant H Chole1 and Swati Balsaraf2*

1Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, Faculty of Dentistry, Najran University, Saudi Arabia
2Department of Public Health Dentistry, Ex-professor, College of Dental Sciences and Hospital, Rau, Indore, India

*Corresponding Author: Swati Balsaraf, Department of Public Health Dentistry, Ex-professor, College of Dental Sciences and Hospital, Rau, Indore, India.

Received: February 15, 2024; Published: February 27, 2024

Abstract

Introduction: Neem Tree (Azardirachta indica) is a common evergreen tree with medicinal values. Neem contains the alkaloid margosine, resins, gum, chloride, fluoride, silica, sulfur, tannins, oils, saponins, flavenoids, sterols, and calcium.

Methodology: Antimicrobial susceptibility testing protocols. Schwalve, Moore and Goodwin, Crc Press 2007 were followed after the extract was prepared. The extract were stored under 5 deg.C. and used for minimum inhibitory concentration (MIC) determination in comparision with Chlorhexidine as standard.

Results: The extracts of Neem bark were tested for minimum inhibitory concentration against A. viscosus, L. acidophilus and S. mutans. Neem bark extract. s were most effective against A. viscosus as compared to S. mutans and L. acidophilus.

Conclusion: Neem has many medicinal benefits apart from antibacterial activity. The current study paves way to study in deep about the antibacterial activity of neem i.e. how does it works on biomolecular level.

Keywords: Neem; BHI; Lactobacillus Acidophillus; Chlorhexidin

References

    1. Prashant GM., et al. “The effect of mango and neem extract on four organisms causing dental caries: Streptococcus mutans, Streptococcus salivavius, Streptococcus mitis, and Streptococcus sanguis: An in vitro study”. Indian Journal of Dental Research4 (2007).
    2. Ranjit R Raut., et al. “Antimicrobial activity of Azadirachta indica (Neem) against Pathogenic Microorganisms”. Journal of Academia and Industrial Research (JAIR)7 (2014).
    3. Santosh KS., et al. “Phytochemicals of Azadirachta Indica Source of Active Medicinal Constituent Used for Cure of Various Diseases: A Review”. Journal of Scientific Research1 (2020).
    4. “Antimicrobial susceptibility testing protocols”. Schwalve, Moore and Goodwin, Crc Press (2007).
    5. Bansal V., et al. “Assessment of antimicrobial effectiveness of neem and clove extract against Streptococcus mutans and Candida albicans: An in vitro study”. Nigerian Medical Journal 60 (2019): 285-289.
    6. Isha Jain., et al. “Comparative Evaluation of Antibacterial Efficacy of Six Indian Plant Extracts against Streptococcus Mutans”. Journal of Clinical and Diagnostic Research 2 (2015): ZC50–ZC53.
    7. Raja RRY., et al. “Antimicrobial activity of Azadirachta Indica (neem) leaf, bark and seed extracts”. International Journal of Research In Phytochemical And Pharmacological Sciences 1 (2013): 1-4.
    8. A Muhammad., et al. “Antimicrobial Activity of Azadirachta indica (Neem) Leave Extract Against Some Clinical Isolates”. DUJOPAS 1b (2019): 97-104.
    9. Nayak Aarat., et al. “Evaluation of antibacterial and anticandidial efficacy of aqueous and alcoholic extract of Neem an in-vitro study”. International Journal of Research in Ayurveda and Pharmacy 1 (2011): 230-235.

    Citation

    Citation: Revant H Chole and Swati Balsaraf. “Antibacterial Efficacy of Azardirachta indica (Neem) Against Oral Microorganisms- An In-vitro Study".Acta Scientific Microbiology 7.3 (2024): 97-100.

    Copyright

    Copyright: © 2024 Revant H Chole and Swati Balsaraf. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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