Acta Scientific Microbiology

Research Article Volume 7 Issue 1

Herbal as an Adjunct to Scaling and Root Planning (SRP) in Nonsurgical Periodontitis Treatment in Adult: A Systematic Review of Randomized Controlled Trials

Janaína Escudero1, Mônica Ghislaine Oliveira Alves2,3, Janete Dias Almeida1, Nídia Castro dos Santos4, Huda Gomaa5,6, Erica A Suzumura7, Camila Batista da Silva3, Claudio Pereira Kawakami1, Eliseu Gabriel Faustino1, Beatriz Venturoso Simões1, João Vitor da Silva Rodrigues1, Luis Eduardo Leite1, Camilla Tajzler8, Eliane Chaves Jorge9, Maria Aparecida Neves Jardini10, Marianne Spalding1 and Regina El Dib1,11*

1Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, Universidade Estadual Paulista, São José dos Campos, Brazil
2Universidade Anhembi-Morumbi, Campus São José dos Campos, São Paulo, SP, Brazil
3School of Dentistry, Universidade Mogi das Cruzes, Mogi das Cruzes, Brazil
4Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil
5High Institute of Public Health-Alexandria University, Egypt
6Drug Information Center, Tanta Chest Hospital, Tanta, Egypt
7Departament of Preventive Medicine, Faculdade de Medicina - FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
8Department of Surgery, McMaster University, St. Joseph's Healthcare, Hamilton, Canada
9Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, Brazil 10Department of Diagnosis and Surgery, School of Sciences and Technology, UNESP - Universidade Estadual Paulista, São José dos Campos, Brazil
11McMaster Institute of Urology, McMaster University, St. Joseph’s Healthcare, Hamilton, Canada

*Corresponding Author: Regina El Dib, Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, Universidade Estadual Paulista, São José dos Campos, Brazil.

Received: November 27, 2023; Published: December 26, 2023

Abstract

Background: Periodontitis is an inflammatory disease that affecting people worldwide. The herbal medications might act as adjuvant or to be an alternative therapy in nonsurgical periodontitis treatment in adult.

Objective: To summarize the effects of herbal medications as an adjunct to scaling and root planning (SRP) or chlorhexidine compared to the standard of care (SRP alone) in adult periodontitis treatment.

Methods: Searches of MEDLINE, EMBASE, CENTRAL, LILACS and ISI Web of Science up to March 2019 were performed to identify randomized controlled trials (RCTs). We used the GRADE approach to rate overall certainty of the evidence by outcome.

Results: 30 randomized trials including 1,125 patients proved eligible. Pooled results from five RCTs showed a statistically significant difference in favor of herbal medicine as an adjunct to SRP when compared to SRP alone in reducing probing pocket depth (PPD) (Mean Difference (MD) -0.46, 95% Confidence Interval (CI) -0.67 to -0.26, p < 0.00001; I2 = 38%, p = 0.17, n = 166).

Conclusions: Some possible clinically meaningful differences between herbal medicine as an adjunct to SRP and other comparisons exist, but no definitive conclusions can be drawn from these findings. Low-certainty evidence indicates that combination therapy with herbal medicine plus SRP is more effective than SRP alone to reduce PPD in adult with periodontitis.

Keywords: Herbal Medicine; Periodontitis; Randomized Controlled Trials; Systematic Review; GRADE

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Citation

Citation: Regina El Dib., et al. “Herbal as an Adjunct to Scaling and Root Planning (SRP) in Nonsurgical Periodontitis Treatment in Adult: A Systematic Review of Randomized Controlled Trials".Acta Scientific Microbiology 7.1 (2024): 44-58.

Copyright

Copyright: © 2024 Regina El Dib., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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