Janaína Escudero¹, Mônica Ghislaine Oliveira Alves^2,3, Janete Dias Almeida¹, Nídia Castro dos Santos⁴, Huda Gomaa^5,6, Erica A Suzumura⁷, Camila Batista da Silva³, Claudio Pereira Kawakami¹, Eliseu Gabriel Faustino¹, Beatriz Venturoso Simões¹, João Vitor da Silva Rodrigues¹, Luis Eduardo Leite¹, Camilla Tajzler⁸, Eliane Chaves Jorge⁹, Maria Aparecida Neves Jardini¹⁰, Marianne Spalding¹ and Regina El Dib^1,11*

¹Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, Universidade Estadual Paulista, São José dos Campos, Brazil
²Universidade Anhembi-Morumbi, Campus São José dos Campos, São Paulo, SP, Brazil
³School of Dentistry, Universidade Mogi das Cruzes, Mogi das Cruzes, Brazil
⁴Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil
⁵High Institute of Public Health-Alexandria University, Egypt
⁶Drug Information Center, Tanta Chest Hospital, Tanta, Egypt
⁷Departament of Preventive Medicine, Faculdade de Medicina - FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
⁸Department of Surgery, McMaster University, St. Joseph's Healthcare, Hamilton, Canada
⁹Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, Brazil ¹⁰Department of Diagnosis and Surgery, School of Sciences and Technology, UNESP - Universidade Estadual Paulista, São José dos Campos, Brazil
¹¹McMaster Institute of Urology, McMaster University, St. Joseph’s Healthcare, Hamilton, Canada

*Corresponding Author: Regina El Dib, Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, Universidade Estadual Paulista, São José dos Campos, Brazil.

Received: November 27, 2023; Published: December 26, 2023

Abstract

Background: Periodontitis is an inflammatory disease that affecting people worldwide. The herbal medications might act as adjuvant or to be an alternative therapy in nonsurgical periodontitis treatment in adult.

Objective: To summarize the effects of herbal medications as an adjunct to scaling and root planning (SRP) or chlorhexidine compared to the standard of care (SRP alone) in adult periodontitis treatment.

Methods: Searches of MEDLINE, EMBASE, CENTRAL, LILACS and ISI Web of Science up to March 2019 were performed to identify randomized controlled trials (RCTs). We used the GRADE approach to rate overall certainty of the evidence by outcome.

Results: 30 randomized trials including 1,125 patients proved eligible. Pooled results from five RCTs showed a statistically significant difference in favor of herbal medicine as an adjunct to SRP when compared to SRP alone in reducing probing pocket depth (PPD) (Mean Difference (MD) -0.46, 95% Confidence Interval (CI) -0.67 to -0.26, p < 0.00001; I2 = 38%, p = 0.17, n = 166).

Conclusions: Some possible clinically meaningful differences between herbal medicine as an adjunct to SRP and other comparisons exist, but no definitive conclusions can be drawn from these findings. Low-certainty evidence indicates that combination therapy with herbal medicine plus SRP is more effective than SRP alone to reduce PPD in adult with periodontitis.

Keywords: Herbal Medicine; Periodontitis; Randomized Controlled Trials; Systematic Review; GRADE

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Citation

Citation: Regina El Dib., et al. “Herbal as an Adjunct to Scaling and Root Planning (SRP) in Nonsurgical Periodontitis Treatment in Adult: A Systematic Review of Randomized Controlled Trials".Acta Scientific Microbiology 7.1 (2024): 44-58.

Copyright

Copyright: © 2024 Regina El Dib., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.