Ferez S Nallaseth*

Founding President, CEO, CSO and CFO for the LSINJ, USA

*Corresponding Author: Ferez S Nallaseth, Founding President, CEO, CSO and CFO for the LSINJ, USA.

Received: August 09, 2023; Published: August 18, 2023

Comparative evaluations of key policy decisions detracting from and confronting the conceptual necessity for initiating the combinatorial approach in real time operations (CA RTO) for preempting genetic disease lesions including the Mutome are summarized here (Figures 1-4), [1-3]. The harnessing of Evolutionary Genetics of Speciation (EGS) and specifically ‘Hybrid Incompatibility’ and its wider generational manifestation ‘Species Incompatibility’ in combination with the resolving power of contemporary methods, permit the elucidation and preemption of mechanistically relevant failures of networks of genes that maintain genomes as e.g., with CA RTO. EGS and ‘Species Incompatibility’ can permit the single generational induction and deployment of the full spectrum of adaptations and mutations, representing ~4 billion years of speciation yielding all current biological systems including those maintaining and repairing the genome. They can be identified and elucidated by nonselective ‘panning’ followed by associated analytical systems of increasing resolution, precision, rate and throughput (Figures 2-4) [1,2-5].

Keywords Mutations, calculated (MCMEPPPL), preemption of genetic diseases, Species Incompatibility, High Resolution-Precision-Content Analysis, CA RTO system, WWII & SALT, vs Genetics/Epigenetics debate, Crop Failures & Famines

References

1. Nallaseth FS. “Parallels between existential consequences of decisions enforcing the current paradigm in healthcare to the exclusion of CA RTO and those made in the Cold War, ASM” (2023).
2. Nallaseth FS. “Switching the paradigm in medicine from management of genetic lesions & their pathology(s) to preemption, webinar at San Joaquin Valley Delta College, Stockton, California (2019).
3. Ferez Soli Nallaseth., et al. “Akin to the Great Revolutions or Ages, the Combinatorial Approach for Preempting Genetic Diseases Requires the Confluence of Independent Scientific and Societal Developments Emerging from Synergisms Between Serendipitous, Planned and Natural Progressions Significantly Magnifying the Impact Over the Simple Sum of their Individual Components or Subfields”. Acta Scientific Microbiology9 (2021).
4. Nallaseth FS. “Shifting the therapeutic paradigm in medicine from post mutational (and pathological) intervention to preemption - a synopsis of the ‘nuts and bolts”. MOJ Proteomics and Bioinformatics2 (2019): 1-840.
5. Nallaseth FS. “Is there a role for an evolutionary genetics based rational health policy In Global Biomedical, Health and Economic Policies?” Molecular Biology: Open Access 3 (2021): 1.
6. Nallaseth FS. “Sequence instability and functional inactivation of murine Y chromosomes can occur on a specific genetic background”. Molecular Biology and Evolution2 (1992):331-365.
7. Jerry A Coyne and H Allen Orr. “Sinauer Associates is an imprint of Oxford University Press (2004).

Citation

Citation: Ferez S Nallaseth. “Parallels between Existential Consequences of Decisions Enforcing the Current Paradigm in Healthcare to the Exclusion of CA RTO and those Made in the Cold War". Acta Scientific Microbiology 6.9 (2023): 66-72.

Copyright

Copyright: © 2023 Ferez S Nallaseth. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.