Attapon Cheepsattayakorn1,2*, Ruangrong Cheepsattayakorn3 and Porntep Siriwanarangsun1
1Faculty of Medicine, Western University, Pathumtani Province, Thailand 210th Zonal Tuberculosis and Chest Disease Center, Chiang Mai, Thailand 3Department of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
*Corresponding Author: Attapon Cheepsattayakorn, 10th Zonal Tuberculosis and Chest Disease Center, Chiang Mai, Thailand.
Received: December 22, 2022; Published: January 01, 2023
Cellular or antibody responses is measured in the most studies of immunity to SARS-CoV-2 (COVID-19) [1]. Nevertheless, if ever SARS-CoV-2 (COVID-19) present in the plasma, the infectious virus is rarely infects the nasal and conjunctival mucosal surfaces [1]. In COVID-19-infected-unvaccinated and unvaccinated-COVID-19-uninfected individuals, the levels of nasal and salivary anti-spike antibody correlated significantly with plasma antibody [1,2]. The reported mean correlations for titers in plasma and saliva for IgG and IgA were moderate (p = 0.55; 95% CI: 0.38-9.73) and weak (p = 0.28; 95% CI: 0.12-0.44), respectively [2]. A previous systematic review demonstrated that previous-COVID-19-infected-vaccinated individuals demonstrated boosting anti-spike antibody levels in the nose or saliva less than in plasma [1].
Citation: Attapon Cheepsattayakorn. “Level Differences of Plasma, Nasal, and Salivary Antibody to SARS-CoV-2 (COVID-19) During Natural Infection and After COVID-19 Vaccination". Acta Scientific Microbiology 6.2 (2023): 01.
Copyright: © 2022 Attapon Cheepsattayakorn. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.