Acta Scientific Microbiology (ISSN: 2581-3226)

Review Article Volume 5 Issue 8

Natural Anti-infective Agents: A Promising Front-line Strategy Against Microbial Resistance Mechanisms

Gloria G Guerrero M1*, Juan M Favela-Hernández2,3, and Aurora Martinez-Romero2

1University Autonome of Zacatecas, Unit of Biological Sciences, Lab of Immunobiology, Campus II, Zacatecas, Zac, Mexico

2Universidad Juárez del Estado de Durango, Facultad de Ciencias Quimicas, México

3Multidisciplinary Institute of Sciences, AVICENA Campus, Torreón, Coahuila, México

*Corresponding Author: Gloria G Guerrero M, University Autonome of Zacatecas, Unit of Biological Sciences, Lab of Immunobiology, Campus II, Zacatecas, Zac, Mexico.

Received: October 04, 2021; Published: July 29, 2022

Abstract

The global emergence of drug-resistant strains is one of the major concerns and challenges in human infectious diseases due mainly to antibiotics misuse and dosage leading to inadequate control of microbial infections. Anti-infective agents represent the new generation of natural antibiotics (chalcones, phenolic acids, bacteriocins, antimicrobial peptides). These compounds show diversity in sources, chemical structures, and mechanisms of action. These capabilities make them potential candidates to fight against microbial resistance. The literature on this topic is immense. This review aims to pinpoint general and basic knowledge of natural anti-infective agents (sources, targets, physicochemical properties), all of which constitute key elements that shape their antimicrobial action and make them a hope for more effective treatments.

Keywords: Anti-infective Agents; Bacteriostatic; Bactericidal; Triterpenes; Flavonoids; Gram Positive/Gran Negative Bacteria; Secondary Metabolites; Antimicrobial Peptides

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Citation

Citation: Gloria G Guerrero M., et al. “Natural Anti-infective Agents: A Promising Front-line Strategy Against Microbial Resistance Mechanisms". Acta Scientific Microbiology 5.8 (2022): 134-148.

Copyright

Copyright: © 2022 Gloria G Guerrero M., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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