Acta Scientific Microbiology (ISSN: 2581-3226)

Editorial Volume 5 Issue 8

Metosartan and its Negative Effects on Male Reproductive Potential

Eswari Beeram*

Assistant Professor, Sree Vidyanikethan Degree College, A.P, India

*Corresponding Author: Eswari Beeram, Assistant Professor, Sree Vidyanikethan Degree College, A.P, India.

Received: May 30, 2022; Published: July 01, 2022


Metosartan is a drug used to treat blood pressure and consists of components Metoprolyl and Temisartan. But it majorly affects male reproductive system organs like testes and male reproductive potential in male wistar rats and as well as humans. Metosartan reduces the sperm count as well as sperm viability in rats and humans and it promotes sperm DNA abberations and inhibits testicular RNase similar to RNase A. Metosartan affects the functioning of mitochondria and chromatin folding in sperms. In vivo studies on rats by using metosartan proved to affect testes histology but it effects on histology of tissues in in vivo is found to be minimal. It causes fusion of double layer membrane of nucleus and affects maturation of nuclear pore seeding complex.



Citation: Eswari Beeram. “Metosartan and its Negative Effects on Male Reproductive Potential". Acta Scientific Microbiology 5.8 (2022): 01 .


Copyright: © 2022 Eswari Beeram. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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