Acta Scientific Microbiology (ISSN: 2581-3226)

Research Article Volume 5 Issue 5

Ficus carica Linn (Moraceae) Fruit's: Qualitative, Quantitative Phytochemical Screening and Antibacterial Activities

Hawa Alsadi1, Mustafa Alsadi2, Fatimh Mustafa Meelad1 and Salma Moftah Alamen3*

1Chemistry Department, Faculty of Education, Elmergib University, Alkhums, Libya
2Food and Drug Control Center, Alkhums, Libya
3Biology Department, Faculty of Education, Elmergib University, Alkhums, Libya

*Corresponding Author: Hawa Alsadi, Chemistry Department, Faculty of Education, Elmergib University, Alkhums, Libya.

Received: March 10, 2022; Published: April 22, 2022


Fig fruit, Ficus carica Linn (F. carica) has natural active chemical constituents that own medicinal properties which enclose a vast scope of biological effects. The extracts of fresh matured of F. carica were used to screen for some active chemical constituents (qualitatively and quantitatively). The screening estimates the phytochemicals among the qualitative tests done for the presence of secondary metabolites; where the results contained in the crude aqueous and alcoholic extracts of F. carica fruits which are Triterpenoids, Steroids, Tannins, Protein, Glycosides, Reducing Sugars, Alkaloids, Flavonoids, Carbohydrates, Sugars, Fats, Fixed Oils, Saponins and vitamin C, where it was found that all the detected components were between medium and rich in presence in both extracts. While the result of weight loss of the fresh F. carica at room temperature was 41g with a percentage yields of 73%. And the results of ash content of fresh fruits were the weight of residual ash after burning 7.637g and the percentage of ash content 76.37%. And the results of the extraction yield percentage of the aqueous extract revealed 87% with a Creamish to Dark Brown and the ethanolic extract was 93% with Greenish Oily in colour. The results of the detected quantitative secondary metabolites of the phytochemicals were revealed that 58, 73, 65, and 53% for Saponins, Terpenoids, Alkaloids and Flavonoids, respectively. The greater percentage amount in fruits was obtained 73% for alkaloids and the lowest 53% was for Flavonoids. In addition, the results of the bioactivity of the aqueous extract against pathogenic bacteria were as follows 12, 13, 15 and 12 mm against each of P. aeruginosa, E. coli, B. subtilis and S. aureus, consequently. Whereas the ethanolic extract was as follows 18, 16, 20 and 17 mm against each of P. aeruginosa, E. coli, B. subtilis and S. aureus, consequently.

Keywords: Ficus carica Linn; Chemical Constituents (Qualitatively and Quantitatively); Antibacterial Activity


  1. Roze LV., et al. “Compartmentalization and molecular traffic in secondary metabolism: a new understanding of established cellular processes”. Fungal Genetics and Biology 48 (2011): 35-48.
  2. The Fig: it’s History, Culture, and Curing, Gustavus A. Eisen, Washington, Govt. print. Off., (1901).
  3. “RHS A-Z encyclopedia of garden plants”. United Kingdom: Dorling Kindersley (2008): 1136.
  4. The Indian Pharamacopoeia 2nd Enden. Government of India publication, New Delhi (1966).
  5. Ingle KP., et al. “Phytochemicals: Extraction methods, identification, and detection of bioactive compounds from plant extracts”. Journal of Pharmacognosy and Phytochemistry 6 (2017): 32-36.
  6. Pandey A and Tripathi S. “Concept of standardization, extraction, and pre-phytochemical screening strategies for herbal drug”. Journal of Pharmacognosy and Phytochemistry 2 (2014): 115-119.
  7. Tiwari P., et al. “Phytochemical screening and extraction: A review”. International Journal of Pharmaceutics 1 (2011): 98-106.
  8. Eloff JN. “Which extractant should be used for the screening and isolation of antimicrobial components from plants”. Journal of Ethnopharmacology 60 (1998): 1-8.
  9. Beena P., et al. “Preliminary phytochemical screening of Cicer arietinum in folklore medicine for hepatoprotection”. Journal of Innovations in Pharmaceutical and Biological Sciences 3 (2016): 153-159.
  10. Trease GE and Evans WC. “Textbook of pharmacognosy”. 13th London, UK; Toronto, Canada; Tokyo, Japan: Bailiere Tindall (1989): 200-201.
  11. Wallis TE. “Text book of pharmacognosy”. Delhi, India: CBS Publishers and Distributors (1989): 356-549. Google Scholar.
  12. Dhawan D and Gupta J. “Comparison of different solvents for phytochemical extraction potential from Datura metel plant leaves”. International Journal of Biological Chemistry 11 (2017): 17-22.
  13. Kenwat R., et al. “Preliminary phytochemical screening and in vitro antioxidant efficacy of fruit oil of Martynia annua”. UK Journal of Pharmaceutical and Biosciences1 (2014): 16-22.
  14. Gupta AK., et al. “Phytochemical Screening and Antimicrobial Assessment of Leaves of Adhatoda vasica, Azadirachta indica and Datura stramonium”. UK Journal of Pharmaceutical and Biosciences1 (2011): 42-47.
  15. Purohit P., et al. “Assessment of antibacterial activity and phytochemical screening of Hemidesmus indicus root extracts”. UK Journal of Pharmaceutical and Biosciences 6 (2014): 67-72.
  16. El-Feky AM., et al. “Phytochemical and Biochemical Studies of Sage (Salvia officinalis L.)”. UK Journal of Pharmaceutical and Biosciences 5 (2016): 56-62.
  17. Ravi K., et al. “Phytochemical Screening and Antibacterial Activity of Ethanol Extract of Leaves and Twigs of Azadirachta indica A. Juss”. UK Journal of Pharmaceutical and Biosciences6 (2015): 56-59.
  18. Sharma A., et al. “Potential biological efficacy of Pinus plant species against oxidative, inflammatory and microbial disorders”. BMC Complementary and Alternative Medicine1 (2015): 35.
  19. Boham BA and Kocipal-Abyazan R. “Flavonoids and condensed tannins from leaves of Hawaiian Vaccinium vaticulatum and V. calycinum”. Pacific Science 48 (1974): 458-463.
  20. Harborne JB. “Phytochemical methods”. 2nd New York 3 (1984): 100-117.
  21. Obadoni BO and Ochuko PO. “Phytochemical studies and comparative efficacy of crude extracts of some homeostatic plants in Edo and Delta States of Nigeria”. Global Journal of Pure and Applied Sciences 8 (2001): 203-208.
  22. Harborne JB. “Phytochemical methods”. London. Chapman and Hall, Ltd. (1973): 49-188.
  23. Subramaniam S., et al. “Bioinformatics and systems biology of the lipidome”. Chemical Reviews10 (2011): 6452-6490.
  24. Güçlü-Üstündağ Ö and Mazza G. “Saponins: Properties, applications and processing”. Critical Reviews in Food Science and Nutrition 47 (2007): 231-258.
  25. Koster R., et al. “Acetic acid for analgesic screening”. Federation Proceedings 18 (1959): 412-418.
  26. Drew WL., et al. “Reliability of the Kirby-Bauer disc diffusion method for detecting methicillin-resistant strains of Staphylococcus aureus”. Applied Microbiology2 (1972): 240-247.
  27. Tchombe LN and Louajri A. “Therapeutic effects of Ficus carica leaves: A brief review”. ARPN Journal of Science and Technology 5 (2015): 37-34.
  28. Badgujar SB., et al. “Traditional uses, phytochemistry and pharmacology of Ficus carica: A review”. Pharmaceutical Biology 52 (2014): 1487-1503.
  29. Mishra AK., et al. “Inhibitory activity of Indian spice plant Cinnamomum zeylanicum extracts against Alternaria solani and Curvularia lunata, the pathogenic dematiaceous moulds”. Annals of Clinical Microbiology and Antimicrobials 8 (2009): 1-7.
  30. Anitha J and Jayraaj IA. “In-vitro antibacterial activity and evaluation of flavonoid and phenol in earthworm powder (eudrilus eugeniae)”. World Journal Pharmacy and Pharmaceutical Science 2 (2013): 4917-4928.
  31. Działo M., et al. “The potential of plant phenolics in prevention and therapy of skin disorders”. International Journal of Molecular Sciences 17 (2016): 1-41.


Citation: Hawa Alsadi., et al. “The Neonates' Body Length and Body Weight in Two Different Periods of Time”.Acta Scientific Microbiology 5.5 (2022): 80-89.


Copyright: © 2022 Hawa Alsadi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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