Acta Scientific Microbiology (ISSN: 2581-3226)

Editorial Volume 5 Issue 5

Risk for Newly Diagnosed Diabetes and Impact of Pre-diabetes and Undiagnosed Diabetes on Severity and Mortality for SARS-CoV-2 Infection

Attapon Cheepsattayakorn1,2*, Ruangrong Cheepsattayakorn3 and Porntep Siriwanarangsun1

1Faculty of Medicine, Western University, Pathumtani Province, Thailand

210th Zonal Tuberculosis and Chest Disease Center, Chiang Mai, Thailand

3Department of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

*Corresponding Author: Attapon Cheepsattayakorn, 10th Zonal Tuberculosis and Chest Disease Center, Chiang Mai, Thailand.

Received: March 23, 2022; Published: March 30, 2022

Hyperglycemia and diabetes are risk factors for critical COVID-19 clinical outcomes [1]. Disproportionately, COVID-19 pandemic has affected increased-risk-of-severe-COVID-19 individuals [2]. During the COVID-19 pandemic, increased in number of type 1 diabetes diagnosed [3,4] and increased frequency and severity of diabetic ketoacidosis (DKA) at the time of diagnosis of diabetes [5] have been demonstrated in European pediatric populations. Independent of diabetic status, pre-diabetes and undiagnosed type 2 diabetes revealed increased risk of severe COVID-19, whereas intrahospital or de novo hyperglycemia predicted critical COVID-19 clinical outcomes [1]. Among individuals aged < 18 years with COVID-19 infection, there was an increased risk for diabetes supported by independent studies in COVID-19 adults [2]. A recent study demonstrated that COVID-19 patients with diabetes presented with more hyperglycemia, whereas type-2-diabetes patients with COVID-19 infection presented with more intensive-care-unit (ICU) need [6]. Another recent study revealed that lower blood glucose concentration, higher inflammatory biomarkers, and ICU admission were associated with diabetes diagnosed at the time of COVID-19 presentation [7].


  1. Vargas-Va´zques A., et al. “Impact of undiagnosed type 2 diabetes and prediabetes on severity and mortality for SARS-CoV-2 infection”. BMJ Open Diabetes Research and Care 9 (2021): e002026.
  2. Barrett CE., et al. “Risk for newly diagnosed diabetes > 30 days after SARS-CoV-2 infection among persons aged < 18 years-United States, March 1, 2020-June 28, 2021”. Morbidity and Mortality Weekly Report2 (2022): 59-65.
  3. Unsworth R., et al. “New-onset type 1 diabetes in children during COVID-19 : multicenter regional findings in the U.K”. Diabetes Care 43 (2020): e170-e171.
  4. Vlad A., et al. “Increased incidence of type 1 diabetes during the COVID-19 pandemic in Romanian children”. Medicina (Kaunas) 57 (2021): 973.
  5. Kamrath C., et al. “Ketoacidosis in children and adolescents with newly diagnosed type 1 diabetes during the COVID-19 pandemic in Germany”. JAMA 324 (2020): 801-804.
  6. Kempegowda P., et al. “Effect of COVID-19 on the clinical course of diabetic ketoacidosis (DKA) in people with type 1 and type 2 diabetes”. Endocrine Connections 10 (2021): 371-377.
  7. Cromer SJ., et al. “Newly diagnosed diabetes vs. pre-existing diabetes upon admission for COVID-19 : associated factors, short-term outcomes, and long-term glycemic phenotypes”. Journal of Diabetes and Its Complications (2022).


Citation: Attapon Cheepsattayakorn., et al. “Risk for Newly Diagnosed Diabetes and Impact of Pre-diabetes and Undiagnosed Diabetes on Severity and Mortality for SARS-CoV-2 Infection". Acta Scientific Microbiology 5.5 (2022): 01-02.


Copyright: © 2022 Attapon Cheepsattayakorn., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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