Attapon Cheepsattayakorn^1,2*, Ruangrong Cheepsattayakorn³ and Porntep Siriwanarangsun¹

¹Faculty of Medicine, Western University, Pathumtani Province, Thailand

*Corresponding Author: Attapon Cheepsattayakorn, 10^th Zonal Tuberculosis and Chest Disease Center, Chiang Mai, Thailand.

Received: March 23, 2022; Published: March 30, 2022

Hyperglycemia and diabetes are risk factors for critical COVID-19 clinical outcomes [1]. Disproportionately, COVID-19 pandemic has affected increased-risk-of-severe-COVID-19 individuals [2]. During the COVID-19 pandemic, increased in number of type 1 diabetes diagnosed [3,4] and increased frequency and severity of diabetic ketoacidosis (DKA) at the time of diagnosis of diabetes [5] have been demonstrated in European pediatric populations. Independent of diabetic status, pre-diabetes and undiagnosed type 2 diabetes revealed increased risk of severe COVID-19, whereas intrahospital or de novo hyperglycemia predicted critical COVID-19 clinical outcomes [1]. Among individuals aged < 18 years with COVID-19 infection, there was an increased risk for diabetes supported by independent studies in COVID-19 adults [2]. A recent study demonstrated that COVID-19 patients with diabetes presented with more hyperglycemia, whereas type-2-diabetes patients with COVID-19 infection presented with more intensive-care-unit (ICU) need [6]. Another recent study revealed that lower blood glucose concentration, higher inflammatory biomarkers, and ICU admission were associated with diabetes diagnosed at the time of COVID-19 presentation [7].

References

1. Vargas-Va´zques A., et al. “Impact of undiagnosed type 2 diabetes and prediabetes on severity and mortality for SARS-CoV-2 infection”. BMJ Open Diabetes Research and Care 9 (2021): e002026.
2. Barrett CE., et al. “Risk for newly diagnosed diabetes > 30 days after SARS-CoV-2 infection among persons aged < 18 years-United States, March 1, 2020-June 28, 2021”. Morbidity and Mortality Weekly Report2 (2022): 59-65.
3. Unsworth R., et al. “New-onset type 1 diabetes in children during COVID-19 : multicenter regional findings in the U.K”. Diabetes Care 43 (2020): e170-e171.
4. Vlad A., et al. “Increased incidence of type 1 diabetes during the COVID-19 pandemic in Romanian children”. Medicina (Kaunas) 57 (2021): 973.
5. Kamrath C., et al. “Ketoacidosis in children and adolescents with newly diagnosed type 1 diabetes during the COVID-19 pandemic in Germany”. JAMA 324 (2020): 801-804.
6. Kempegowda P., et al. “Effect of COVID-19 on the clinical course of diabetic ketoacidosis (DKA) in people with type 1 and type 2 diabetes”. Endocrine Connections 10 (2021): 371-377.
7. Cromer SJ., et al. “Newly diagnosed diabetes vs. pre-existing diabetes upon admission for COVID-19 : associated factors, short-term outcomes, and long-term glycemic phenotypes”. Journal of Diabetes and Its Complications (2022).

Citation

Citation: Attapon Cheepsattayakorn., et al. “Risk for Newly Diagnosed Diabetes and Impact of Pre-diabetes and Undiagnosed Diabetes on Severity and Mortality for SARS-CoV-2 Infection". Acta Scientific Microbiology 5.5 (2022): 01-02.

Copyright

Copyright: © 2022 Attapon Cheepsattayakorn., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.