Examining the Efficacy of Clomiphene Citrate as a Treatment for Male Infertility
Rohan Rai*
Junior at Clements High School in Sugar Land, Texas, United States
*Corresponding Author: Rohan Rai, Junior at Clements High School in Sugar Land, Texas, United States.
Received:
February 07, 2022; Published: March 28, 2022
Abstract
The infertility rates in adult males have been rising at an alarming rate in recent years. Studies have shown that sperm counts have declined more than 59% in the past 50 years among men throughout North America, Europe, and Australia. The recent emergence of COVID-19 has further increased male fertility concerns, with studies evidencing potential damage the virus could inflict upon the testes. While it is not clear yet whether these developments have any major implications on the future of the human race as a whole, couples around the world struggle to come to terms with the fact that a biological child is not an option for them. The majority of these cases are a result of functional hypogonadism, a condition where infertility is caused by a secondary factor such as hormone abnormalities, obesity, and chronic illnesses, rather than an impaired hypothalamic-pituitary-testicular axis. Clomiphene citrate is a treatment for functional hypogonadism that has yet to be approved by the FDA for men, but has shown promising results in clinical trials and is used off-label. This project analyzes the recently emerging drug of as a gonadotropin-inducer in men by corroborating existing research to find causations and interviewing a user of the drug for his experiences. An educated claim (with limitations considered) is then made to identify whether the treatment is safe and effective and an ideal patient target and dosage is stated.
Keywords:COVID-19; Infertility; FDA
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