Basant Kumar Sinha¹* and Anshu Singh²

¹Ex Professor and Head [Microbiology], Bihar Veterinary College, Patna, Bihar and Guest Faculty [Microbiology], Indian Institute of Health Education and Research, Patna, Bihar and [Biotechnology], Anugrah Narayan College, Patna, Bihar, India

²PG Student (Sports Physiotherapy), Garden City University, Bangalore, Karnataka, India

*Corresponding Author: Basant Kumar Sinha, Ex Professor and Head [Microbiology], Bihar Veterinary College, Patna, Bihar, India.

Received: December 23, 2021; Published: March 03, 2022

Abstract

Myasthenia gravis is caused by a breakdown in the normal communication between nerve and muscles. In this disease neurotransmission is impaired by antibodies against the acetylcholine receptors in the post-synaptic membrane of the muscle. It is considered to be an organ specific autoimmune disease and also due to the thymic abnormalities. In this disease there is weakness of leg and arm muscles, double vision, drooping eyelids and difficulties with speech, chewing, swallowing and breathing. As there is no specific treatment of myasthenia gravis, so physiotherapeutic management can reduce sign and symptoms. However, suppression of production of cyclohexamide receptor antibodies by administrating corticosteroid and immunosuppressive drugs like prednisolone and azoathioprine etc. help in improving myaesthenia gravis. As in some cases, thymoma are frequently associated with autoimmunity so thymectomy may cause reduction of myasthenia gravis as it decreases plasma cell producing antibodies. Because of the various treatment there is marked reduction in the myasthenia gravis.

Keywords:Myaesthenia Gravis; Acetylcholine; Neurotransmission; Thymus; Thymoma; Thymectomy; Immunosuppression; Autoimmunity; Autoantibodies; Neuromuscular

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Citation

Citation: Basant Kumar Sinha and Anshu Singh. “Myasthenia Gravis and its Physiotherapeutic Management". Acta Scientific Microbiology 5.4 (2022): 06-11.

Copyright

Copyright: © 2022 Basant Kumar Sinha and Anshu Singh. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.