Biosynthesized of Silver Nanoparticles from Myrtus communis Leaves and Investigates of their
Antimicrobial Activities Against a Clinical Isolate of Acinetobacter baumannii
Dana Khdr Sabir1*, Karzan R Sidiq1,2, Pyman M Mohamedsalih1 and Nabaz R Khwarahm3
1Department of Medical Laboratory Sciences,College of Medicals and Applied
Sciences, Charmo University,46023 Chamchamal, Kurdistan Region, Iraq
2Department of Medical Laboratory Science, College of Science, Komar University of Science and Technology, Sulaymani 46002, Kurdistan Region, Iraq
3Department of Biology, College of Education, University of Sulaimani, Sulaimani, Kurdistan Region, Iraq
*Corresponding Author: Dana Khdr Sabir, Department of Medical Laboratory
Sciences, Charmo University, Sulaimani, Kurdistan Region, Iraq.
January 12, 2022; Published: February 18, 2022
Multidrug resistant (MDR) bacteria are one of the major concerns of the healthcare system in the twenty-first century. Silver nanoparticles (Ag-NPs) have a great potential to be used as new antimicrobials agents to overcome this global issue. In this study, Ag-NPs were biologically synthesized using the aqueous extract of myrtus (Myrtus communis) leaves as a reducing agent. The biosynthesized of Ag-NPs were firstly characterized using UV-visible spectroscopy, X-ray diffractometry (XRD), and Scanning Electron Microscopy (SEM). The absorbance maximum of Ag-NPs was found at 410 nm, and the particles have spherical and/or irregular shapes with an average size of 19 ± 3 nm. The antibacterial activity of the Ag-NPs was then tested against a clinical strain of Acinetobacter baumannii, isolated from a hospitalized burnt patient in the city of Sulaimani-Iraq. Interestingly, the synthesized Ag-NPs were able to inhibit the growth of isolate at the concentration of 0.2 mg/ml. The results of this study suggest a potential antimicrobial activity of biologically synthesized Ag-NPs against MDR bacteria.
Keywords:Acinetobacter baumannii; Silver Nanoparticles; Antibiotic Resistance; Nosocomial Infections
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