Comparative Analysis of Community Acquired Methicillin-resistant Staphylococcus aureus Nasal Carriage in Eastern Province of Saudi Arabia
Baraa A Amir1, Ali A Rabaan2-4 and Salwa S Sheikh5*
1College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
2Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia
3College of Medicine, Alfaisal University, Riyadh, Saudi Arabia
4Department of Public Health and Nutrition, The University of Haripur, Haripur, Pakistan
5Pathology Services Division, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia
*Corresponding Author: Salwa S Sheikh, Pathology Services Division, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
November 30, 2021; Published: December 27, 2021
Background: The purpose of this study was to investigate community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) nasal carriage rates among outpatients attending a hospital in the Eastern Province of Saudi Arabia. Additionally, this study involved a literature review for comparison of data between different parts of Saudi Arabia and of the Saudi average to the USA and other countries.
Methods: Duplicate nasal swabs from 3188 outpatients attending Johns Hopkins Aramco Healthcare Center in Dhahran in the Eastern Province of Saudi Arabia between January 2013 and December 2014 were tested using Xpert MRSA-SA Nasal Complete G3 kits (Cepheid). A literature review was also conducted using Pubmed, Google Scholar, and Cochrane Library regarding MRSA nasal carrier status.
Results: Nine hundred and thirty-one patients (29.2%) were nasal S. aureus carriers, of which 121 (3.8% overall; 13% of S. aureus carriers) were colonized by CA-MRSA. Our measured CA-MRSA levels were lower than those observed in smaller studies from north-central or central Saudi Arabia, but comparable to levels observed among pediatric outpatients from Riyadh.
Conclusion: Overall Saudi levels were higher than for countries including the United States and European countries. Targeted public health strategies to address CA-MRSA levels in Saudi Arabia are indicated.
Keywords: CA-MRSA; Saudi Arabia; Staphylococcus aureus; Xpert MRSA-SA Nasal Complete
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