Acta Scientific Microbiology (ISSN: 2581-3226)

Review Article Volume 4 Issue 10

Leptospirosis: A Neglected Zoonosis of Public Health Concern

Mahendra Pal1*, Adugna Girma Lema2 and Harsh Kumar Sharma3

1Narayan Consultancy on Veterinary Public Health and Microbiology, Anand, Gujarat, India
2Yemalog Walal Woreda Livestock and Fishery Development and Resource Office, Kellem Wollega Zone, Oromia, Ethiopia
3Department of Veterinary Public Health and Epidemiology, Sher-e-Kashmir University of Agricultural Sciences and Technology, Jammu, India

*Corresponding Author: Mahendra Pal, Professor, Founder Director of Narayan Consultancy on Veterinary Public Health and Microbiology, Anand, Gujarat, India.

Received: August 06, 2021; Published: September 23, 2021

Citation: Mahendra Pal., et al. “Leptospirosis: A Neglected Zoonosis of Public Health Concern". Acta Scientific Microbiology 4.10 (2021): 75-79.

Abstract

  Leptospirosis is an important emerging and re-emerging zoonotic disease that is spread worldwide by pathogenic species of the bacterium genus Leptospira. The disease is commonly reported especially in tropical and subtropical areas. Leptospirosis is a neglected tropical zoonotic disease that is rapidly becoming a major public health issue around the world. Leptospirosis has emerged as a prominent cause of acute febrile disease in many developing nations due to neglect, rapid, unplanned urbanization, and poor sanitation. Although it has been stated that leptospirosis is the most frequent zoonotic illness, it is thought to be underreported due to the non-specificity of clinical symptoms and the lack of laboratory confirmation in endemic areas. A wide range of clinical manifestations, ranging from asymptomatic infection to fulminant, deadly disease, is characteristic of the disease. Laboratory help is needed to confirm an unequivocal diagnosis of leptospirosis. Antibacterial antibiotics are used to treat the acute illness in the patient. This mini review includes all current information on leptospirosis, including its etiology, transmission, clinical symptoms, diagnosis, treatment, and preventative measures.

Keywords: Leptospirosis; Neglected Zoonosis; Public Health; Reservoir; Worldwide

Bibliography

  1. Mullan S and Panwala TH. “Polymerase chain reaction: An important tool for early diagnosis of leptospirosis cases”. Journal Clinical and Diagnostic Research 10 (2016): 8-11.
  2. Trott DJ., et al. “Antimicrobial resistance in Leptospira, Brucella, and other rarely investigated veterinary and zoonotic pathogens”. Journal of Microbiology Spectrum 6 (2018): 4.
  3. Pal M. “Leptospirosis: A contemporary zoonosis”. The Veterinarian 20 (1996): 11-12.
  4. Perez J and Goarant C. “Rapid Leptospira identification by direct sequencing of the diagnostic PCR products in New Caledonia”. Jornal of Biomedical and Microbiology 10 (2011): 325.
  5. Costa F., et al. “Global morbidity and mortality of leptospirosis: A Systematic Review”. PLoS Neglected Tropical Disesase 9 (2015): 1-19.
  6. Pal M., et al. “Leptospirosis and One Health perspective”. American Journal of Public Health Research 9 (2012): 180-183.
  7. Finger M., et al. “Serological and molecular survey of Leptospira spp. among cart horses from an endemic area of human leptospirosis in Curitiba, southern Brazil”. Journal of Revista del Instituto de Medicina 56 (2014): 473-476.
  8. Levett PN., et al. “Leptospirosis review”. Journal of Clinlinical Microbiology 14 (2001): 296-326.
  9. Pratt N., et al. “Leptospira seroprevalence in domestic dogs and cats on the Caribbean Island of Saint Kitts”. Jornal of Veterinary Medicine International 10 (2017): 3.
  10. Safiullah SA., et al. “Laboratory Methods for Diagnosing Leptospirosis : A Review. Bangladish Journal of Medical and Microbiology 3 (2009): 39-43.
  11. Pal M and Hadush A. “Leptospirosis: An infectious emerging water borne zoonosis of global significance”. Air and Water Borne Diseases 6 (2017): 1-4.
  12. Ramli SR., et al. “Discovery of Leptospira spp. seroreactive peptides using ORFeome phage display”. Journal of PLoS Neglected Tropical Disesase 13 (2019): 1-18.
  13. Pal M and Feleke A. “Leptospirosis: A major anthropozoonoic disease of global significance”. International Journal of Livestock Research 2 (2012): 58-67.
  14. Sonja O., et al. “Seroprevalence of cat leptospirosis in Belgrade (Serbia)”. Acta Veterinary Journal 64 (2014): 510-518.
  15. Ram S., et al. “Application of PCR-based DNA sequencing technique for the detection of Leptospira in peripheral blood of septicemia patients”. Malazian Journa of Microbiology 8 (2012): 26-33.
  16. Courdurie C., et al. “Evaluation of different serological assays for early diagnosis of leptospirosis in Martinique (French West Indies)”. Journal of Plos Organization 2 (2017): 1-14.
  17. Goarant C., et al. “Leptospirosis: Risk factors and management challenges in developing countries”. Journal of Reproductive Tropical Medicine 7 (2016): 49-62.
  18. Djelouadji Z., et al. “Overview of laboratory methods to diagnose Leptospirosis and to identify and to type leptospires”. Journal of International Microbiology 20 (2017): 184-193.
  19. Pal M. “Zoonoses”. 2nd Satyam Publishers, Jaipur, India (2007).
  20. Perez J and Goarant C. “Rapid Leptospira identification by direct sequencing of the diagnostic PCR products in New Caledonia”. Journal of Biomedical Microbiology 10 (2010): 325.
  21. Londeree WA., et al. “Leptospirosis: the microscopic danger in paradise”. Hawaii Journal of Medical Public Health 73 (2014): 21-23.
  22. Charan J., et al. “Prophylaxis and treatment for leptospirosis: where are the evidences?” National Journal of Physiology and Pharmacology 2 (2012): 78-83.

Copyright: © 2021 Mahendra Pal., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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