Acta Scientific Microbiology (ISSN: 2581-3226)

Review ArticleVolume 4 Issue 10

Role of Colostrum in Immune-Protection and Disease Prevention in Neonates and their Post Natal Life

Ravi Kant Upadhyay*

Department of Zoology, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur, UP, India

*Corresponding Author: Ravi Kant Upadhyay, Department of Zoology, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur, UP, India.

Received: August 16, 2021; Published: September 08, 2021

Citation: Ravi Kant Upadhyay. “Role of Colostrum in Immune-Protection and Disease Prevention in Neonates and their Post Natal Life". Acta Scientific Microbiology 4.10 (2021): 11-17.


  Colostrum is naturally secreted nutritionally rich thick biological fluid that contains various bioactive molecules such as proteins, carbohydrates, fats, hormones, growth factors, vitamins, lectoferrins, and good repertoire of immunoglobulins which play important role in innate immune defense in new born infants. It contains disease protective and growth promoting micro and macronutrients. Colostrum or milk suckling by mammalian new born babies is a unique phenomenon as it passively transfers important growth factors, which are highly essential for maturation and post natal development. Presence of IgA, IgG and IgM in colostrums protects new born babies from gut mucosal microbial infection. It is highly beneficial for health of sport persons and has high therapeutic value. Commercial storage of colostrums can be used for long term treatment of preterm babies, immunocompromised patients and elderly. Hence, sterilize colostrum collection systems be developed for its clinical and therapeutic use. More specially, for preterm babies constitutive colostrum feeds can be generated with infant formula to protect them from microbial gut infection mainly colonizing bacteria at larger scale. Present review is emphasizing benefits of breast feeding in newborn infants and sketches out immune-protective, nutritional and growth promoting properties of colostrums.

Keywords: Colostrum; Nutritional Value; Immunoglobulins; Innate Immune Defense; Disease Prevention and Therapeutic Uses


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Copyright: © 2021 Ravi Kant Upadhyay. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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