Acta Scientific Microbiology (ISSN: 2581-3226)

Review ArticleVolume 4 Issue 6

The CRISPR-Cas System as a Technology to Redefine Industrial Biotechnology

Anirban Goutam Mukherjee1, Uddesh Ramesh Wanjari2*, Sampada Prakash Pendse3, Akruti Amol Ingole4, Piyush Jagdish Balgote5 and Surbhi Balwant Dhoke2

1Department of Biotechnology, School of Bio-Sciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, India
2Department of Biochemistry, Kamla Nehru Mahavidyalaya, Nagpur, Maharashtra, India
3Department of Biochemistry, RTM Nagpur University, Nagpur, Maharashtra, India
4Department of Biotechnology, Priyadarshini Institute of Engineering and Technology, Nagpur, Maharashtra, India
5Molecular Biology and Genetic Engineering, RTM Nagpur University, Nagpur, Maharashtra, India

*Corresponding Author: Uddesh Ramesh Wanjari, Department of Biochemistry, Kamla Nehru Mahavidyalaya, Nagpur, Maharashtra, India.

Received: April 24, 2021; Published: May 17, 2021

Citation: Uddesh Ramesh Wanjari., et al. “The CRISPR-Cas System as a Technology to Redefine Industrial Biotechnology”. Acta Scientific Microbiology 4.6 (2021): 45-52.

  CRISPR technology has revolutionized the field of Industrial Biotechnology, producing numerous miracles. Several CRISPR/Cas9-based methodologies help simple, quick strain development in yeast and investigate their potential for the synchronous presentation of different hereditary alterations, thus promoting and increasing the efficacy of several industrial technologies. CRISPR/Cas9 framework aimed at fast genome altering of Clostridium ljungdahlii is a known wide target intended for business creation and increasing ethanol's productivity from union gas by several folds. CRISPR-Cas frameworks have prospective for numerous microbes designing solicitations and bacterial strain composing inoculation of societies, self-immunity or auto-focused on cells execution, plus the designing or regulator of metabolic paths enhanced biochemical combination. CRISPR-related protein 9 (Cas9), by the RNA-guided endonuclease specifically, stood out for its guarantee in fundamental examination and quality altering built therapeutics. This review focuses on various industrial and pharmaceutical Biotechnology advancements, including the top qualities for CRISPR-Cas frameworks featuring how these highlights can be utilized in the modern scenario.

Keywords: CRISPR; Industrial Biotechnology; RNA-guided; Yeast; Bacteriophages


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Copyright: © 2021 Uddesh Ramesh Wanjari., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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