Acta Scientific Microbiology (ASMI) (ISSN: 2581-3226)

Research Article Volume 4 Issue 2

The Screening for the Antitrypanosomal Potentials of the Extracts of Curcuma longa L.

Muhammad Muhsin Fathuddin1,2* and Rafeedah Fathuddin1

1Department of Microbiology, Ahmadu Bello University, Zaria, Kaduna State, Nigeria
2Department of Microbiology, Kaduna State University, Kaduna, Kaduna State, Nigeria

*Corresponding Author: Muhammad Muhsin Fathuddin, Department of Microbiology, Kaduna State University, Kaduna, Kaduna State, Nigeria.

Received: November 23, 2020; Published: January 30, 2020

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Abstract

Background: Extracts of Curcuma longa rhizome extracts were investigated for their biological activity.

Methodology: The presence of phytochemicals and antitrypanosomal activities were investigated.

Results: The extracts contained the phytochemicals (Alkaloid, Anthraquinone, Carbohydrates, Cardiac Glycosides, Flavonoid, Glycosides, Phenols, Saponin, Steroid, Tannin and Triterpenes) in table 1 and 2. The extracts showed very good activity against the parasite from figure 1, 2 and 3.

Discussion: The presence of the phytochemical confirms their medicinal potentials. The crude extracts of Curcuma longa were analyzed in vitro for trypanocide activity on Trypanosoma brucei brucei at concentration 100.0 mg/ml, 50.0 mg/ml, 25 mg/ml, 12.5 mg/ml and 6.25 mg/ml. The best activity was seen in Petroleum ether extract, followed by the ethanol extract, then Chloroform which was still impressive.

Conclusion: The results obtained from this study show that the turmeric contains potential antimicrobial components which will be of great use for the advancement of remedies by pharmaceutical industries as a therapy against various diseases.

Keywords: Curcuma longa; Petroleum Ether; Chloroform; Ethanol; Antitrypanosomal Activity; Trypanosoma brucei brucei

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Citation

Citation: Muhammad Muhsin Fathuddin and Rafeedah Fathuddin. “The Screening for the Antitrypanosomal Potentials of the Extracts of Curcuma longa L.". Acta Scientific Microbiology 4.2 (2021): 76-81.




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