Acta Scientific Microbiology (ASMI) (ISSN: 2581-3226)

Review Article Volume 3 Issue 12

Nanotoxicology - An Emerging Discipline Evolving from Nanoparticle Risk Assessment

Nida Tabassum Khan1* and Samiullah Khan2

1Department of Biotechnology, Faculty of Life Sciences and Informatics, Balochistan University of Information Technology, Engineering and Management Sciences, Takatu Campus, Quetta, Balochistan
2Department of Biotechnology, Faculty of Life Sciences and Informatics, Balochistan University of Information Technology, Engineering and Management Sciences, Takatu Campus, Quetta, Balochistan

*Corresponding Author: Nida Tabassum Khan, Department of Biotechnology, Faculty of Life Sciences and Informatics, Balochistan University of Information Technology, Engineering and Management Sciences, Takatu Campus, Quetta, Balochistan.

Received: October 24, 2020; Published: November 30, 2020

×

Abstract

  During this era, applications of nanoparticle has exponentially elevated such as being employed in textiles, pharmaceuticals, cosmetics and medicine. Due to their exclusive properties, nanomaterials are now being considered as an empowering domain that serves as the basis for the development of novel nano-based products in the scientific arena and worth millions in the commercial market. However, this perpetual usage of nanoparticles has intensified numerous environmental and health risks. And therefore, requires attentive evaluation in order to analyze their associated toxicological effects. Thus, investigation of their associated toxicity is a requirement. However, the cumulative diversity of nanomaterials requires to exam a diverse group of nano entities for toxicity prediction subsequently making it a challenging task to gather information regarding their potential exposure and probable risk. Previously employed invitro toxicity testing systems were constrained by principled considerations, time and financial accountabilities Therefore, an alternative unconventional computational approach is needed for the evaluation of nanoparticle associated risk. Such computational approaches for risk assessment are characterized as in silico methods that are cost effective and far less time consuming than customary testing systems and serves to develop a sound infrastructure for nanotoxicology studies.

Keywords: Bioactivity; Hazard assessment; In silico; Nanoinformatics; Physiochemical; Surface Functionality

×

References

  1. CDC Advisory. “Discontinuation of Transmission based precautions and disposition of patients with Covid 19 in healthcare settings (Interim guidance) Discharging Covid 19 patients”. CDC (2020).
  2. Applied Biosystems. Taq Path Covid-19 combo kit catalogue (2020).
  3. La Scola B., et al. “Viral RNA load as determined by cell culture as a management tool for discharge of SARS CoV 2 patients from infectious disease wards”. European Journal of Clinical Microbiology and Infectious Diseases 39 (2020): 1059.
  4. Bullard J., et al. “Predicting infectious SARS CoV 2 from diagnostic samples”. Clinical Infectious Diseases (2020): ciaa638.
  5. Singanayagam A., et al. “Duration of infectiveness and correlation with RT PCR cycle threshold values in cases od Covid 19, England January to May 2020”. Eurosurveillance 32 (2020): 2001483.
  6. Binnicker Ma. “Can the SARS CoV 2 PCR cycle threshold value and the time from symptom onset to test predict infectivity?” Clinical Infectious Diseases (2020): ciaa735.
  7. Han MS., et al. “RT PCR for SARS CoV 2 quantitative versus qualitative”. Lancer (2020).
  8. Belabed M. “Virus dissociated from inflammation in fatal Covid 19”. Nature Reviews Immunology 20 (2020): 519.
  9. Pujadas E., et al. “SARS CoV 2 viral load predicts Covid 19 mortality”. Lancet 8 (2020): e70.
  10. Westbalde LF., et al. “SARS CoV 2 viral load predicts mortality in patients with or without cancer who are hospitalized with Covid 19”. Cancer Cell 38 (2020): 1.
  11. Liu Y., et al. “Viral dynamic in mild and severe cases of Covid 19”. The Lancet Infectious Diseases (2020).
×

Citation

Citation: Nida Tabassum Khan and Samiullah Khan. “Nanotoxicology - An Emerging Discipline Evolving from Nanoparticle Risk Assessment".Acta Scientific Microbiology 3.12 (2020): 124-127.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days

Indexed In






News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is October 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US