Acta Scientific Microbiology (ASMI) (ISSN: 2581-3226)

Research Article Volume 3 Issue 10

The Role of Xenobiotic Enzyme Genes of the First and Second Phases in the Pathogenesis of Fetal Growth Restriction Syndrome

Mavlyanova NN*

Republican Specialized Scientific and Practical Medical Center of Obstetrics and Gynecology Under the Ministry of Health of the Republic of Uzbekistan, Uzbekistan

*Corresponding Author: Mavlyanova NN, Republican Specialized Scientific and Practical Medical Center of Obstetrics and Gynecology Under the Ministry of Health of the Republic of Uzbekistan, Uzbekistan.

Received: June 16, 2020; Published: September 30, 2020

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Abstract

  The article presents the results of molecular genetic studies of genes of biotransformation enzymes of xenobiotics of the first and second phase in pregnant women with fetal growth restriction syndrome. Using the del/del genotype variants of the GSTM1 and GSTT1 genes and G alleles of the GSTP1 gene, one can determine the prognosis of the risk of developing fetal loss syndrome, characterized by impaired detoxification during pregnancy.

Keywords: GSTM1; GSTT1; Fetal Growth Restriction Syndrome (FGRS)

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Citation

Citation: Mavlyanova NN. “The Role of Xenobiotic Enzyme Genes of the First and Second Phases in the Pathogenesis of Fetal Growth Restriction Syndrome". Acta Scientific Microbiology 3.10 (2020): 84-89.



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