Generally, the immunity development that responds to a pathogenic microorganism occurs around 1 - 2 weeks with a non-specific innate response followed by body producing antibodies (humoral responses), immunoglobulins in combination with production of T-cells or cellular immunity. The virus in the body will be eliminated by this combined adaptive response. The definitive viral elimination by their protective role from viral reinfection is yet unidentified. Around eighty known distinct genotypical variants of SARS-CoV-2 (COVID-19) have been identified. Several previous studies demonstrated that SARs-CoV-2 (COVID-19) can persistently present in the feces of the patients, whereas no oral-fecal transmission markers were identified. A previous study in Beijing, China revealed that the virus can persist in the sputum for 39 days after becoming pharyngeal-swab negative. IgM-negative, IgG-positive antibody response and non-detectable viral ribonucleic acid (RNA) after discharging and consequent positive-SARS-CoV-2 (COVID-19)-RNA test, remained negative IgM, and positive IgG antibody tests was demonstrated in three readmitted asymptomatic-COVID-19 patients in Tongji Hospital, China. Due to the highest titers of SARS-CoV-2 RNA reaching within 7 - 10 days of clinical symptom onset and declining thereafter, the upper respiratory tract (posterior nasopharyngeal tonsil region) swabs should be performed.

References

Citation

Citation: Attapon Cheepsattayakorn and Ruangrong Cheepsattayakorn. “Reality of COVID-19 Reinfection". Acta Scientific Microbiology 3.9 (2020): 01-02.

Copyright

Copyright: © 2020 Attapon Cheepsattayakorn and Ruangrong Cheepsattayakorn. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.