Acta Scientific Microbiology (ASMI) (ISSN: 2581-3226)

Review Article Volume 3 Issue 8

Novel Corona Virus COVID-19: An Overview

Rohini Agrawal, Prashant Amale, Shilpa A Deshpande*, Priti Bhoyar, Kiran Gomkale and Sunchuwar

Priyadarshini J. L. Chaturvedi College of Pharmacy, Electronic Zone Building, MIDC, Nagpur, Maharashtra, India

*Corresponding Author: Shilpa A Deshpande, Priyadarshini J. L. Chaturvedi College of Pharmacy, Electronic Zone Building, MIDC, Nagpur, Maharashtra, India.

Received: May 26, 2020; Published: July 30, 2020



 Corona Virus Disease of 2019 (COVID-19), was proclaimed as a pandemic emergency by World Health Organisation (WHO) in March 2020. The main causative factor behind the pneumonic viral infection is Severe Acute Respiratoty Syndrome Coronavirus - 2 (SARS-CoV-2) which holds the 75 - 80% nucleotide sequence similarity with SARS-CoV. Infected and asymptomatic individual are the primary source of human to human transmission due to it become a pandemic, the women with third trimester is also susceptible to this respiratory and pneumonic infection. The time period for the infection is 14 days and the average duration is of 20 days. The infection is clinically manifested mainly by fever, shortness of breath, Acute Respiratory Distress Syndrome (ARDS) etc. Various diagnostic approaches such as Nucleic Acid Amplification Test (NAAT) by using RT-PCR, serological testing etc had been used among which RT-PCR found to be successful in the detection of strain of SARS-CoV-2. Present review focus on the genomic structure of SARS-CoV-2, mechanism, transmission, entry into the host cell, diagnosis, and prevention of the Covid-19. This may be helpful for the development of therapeutic agents used for prophylaxis and treatment of SARS-CoV-2.

Keywords: Covid-19; Corona Virus; WHO; SARS-CoV-2; RT-PCR



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Citation: Shilpa A Deshpande., et al. “Novel Corona Virus COVID-19: An Overview". Acta Scientific Microbiology 3.8 (2020): 112-116.


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