Vikas Jha1*, BS Ajit Kumar2, Sampurna Panigrahi3, Gayatri Nair3 and Nikitha Bangera3
1National Facility of Biopharmaceutical, Mumbai, India
2V.P.M's R. Z. Shah College Mulund, India
2School of Biotechnology and Bioinformatics, DY Patil University, CBD Belapur, Navi Mumbai, India
*Corresponding Author: Vikas Jha, National Facility for Biopharmaceuticals, Mumbai, India.
Received: June 30, 2020; Published: July 25, 2020
There in an increase in demand for reliable, inexpensive and rapid drug susceptibility assay because of expanding anti-tuberculosis drug-resistant Mycobacterium tuberculosis necessitating the need for appropriate treatment. One of the major challenges being faced is the lack of resources and the limiting of reliable drug susceptibility test meeting acceptable levels only for isoniazid and rifampicin. In this article, an overview of different drug susceptibility testing and assays is detailed and the advantages and disadvantages highlighted. It discusses the perspective on conventional methods which have paved the way for modern DSTs along with the advancements made in the conventional methods.
Keywords: Drug Susceptibility; Anti-tuberculosis; Mycobacterium tuberculosis; Conventional DST’s
Citation: Vikas Jha., et al. “An Overview of the Drug Susceptibility Testing for Tuberculosis". Acta Scientific Microbiology 3.8 (2020): 47-56.
Copyright: © 2020 Vikas Jha., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.