Abstract

 Acinetobacter spp. is an important nosocomial pathogen especially in intensive care settings and is resistant to commonly available antimicrobial agents. Active surveillance is therefore necessary in order to determine appropriate antibiotic for the treatment. The purpose of this study was to determine the antibiogram of Acinetobacter spp. isolated in patients attending the tertiary care hospital. It is a prospective study conducted in the Department of Microbiology, Sharda Hospital.

Acinetobacter from various clinical samples were included in this study during six months period from May 2019 to October 2019. The isolates were identified using conventional and automated methods (Vitek2 COMPACT, bioMérieux) and the susceptibility was done using the Kirby-Bauer disk diffusion assay. During the study period, a total of 40 Acinetobacter spp. were isolated from various clinical specimens, out of which 47.5% isolation was from ICUs. Highest isolation was observed from pus samples (22.5%) followed by blood (17.5%) and endotracheal aspirate (17.5%). 77.5% isolates were MDR (Multidrug Resistant), however they remained susceptible to colistin and tetracycline. It is necessary to regularly monitor the resistance phenotypes of Acinetobacter. Enhanced surveillance of MDR Acinetobacter is critical for guiding the rational use of antibiotics and reducing the incidence of hospital acquired infections.

Keywords: Acinetobacter spp; Multi-Drug Resistance (MDR); ICU; Antibiotic Susceptibility

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Citation

Citation: B Apoorva. “Antibiogram of Acinetobacter spp. Isolates in a Tertiary Care Hospital: A Lead towards Antibiotic Stewardship". Acta Scientific Microbiology 3.5 (2020): 71-76.

Copyright

Copyright: © 2020 B Apoorva. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.