Acta Scientific Microbiology (ASMI) (ISSN: 2581-3226)

Research Article Volume 3 Issue 4

Prevalence and Outcome of Asymptomatic Bacteriuria among Antenatal Women in a Tertiary Care Centre

M Sujatha1, D Sudhamadhuri2 and P Prithivi3*

1Third Year Post graduate, Department of Microbiology, Osmania Medical College, India
2Associate Professor, Department of Microbiology, Niloufer Hospital for Woman and Children, India
3Assistant Professor, Department of Obstetrics and Gynaecology, Niloufer Hospital for Women and Children, India

*Corresponding Author: Sudhamadhuri, Associate Professor, Department of Microbiology, Niloufer Hospital for Woman and Children, India.

Received: February 24, 2020; Published: March 12, 2020

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Abstract

  Asymptomatic bacteriuria (ASB) is common in pregnancy due to hormonal and physiological changes causing urinary stasis. ASB may cause maternal complications like Acute Pyelonephritis, PET, PROM, PPROM, PTL and foetal complications like LBW, IUGR and perinatal death.

  This study was conducted to know the prevalence and outcome of ASB among antenatal women attending OPD in a tertiary care hospital. A total of 100 women with no clinical history of UTIs were included in the study for six months, followed up till delivery and discharge. Clean catch mid- stream urine was collected aseptically and processed by standard conventional bacteriological techniques. Out of 100 samples processed, 47 (47%) showed Significant bacteriuria (>105 CFU/ml) with infection rate of 47%. Organisms isolated were Staphylococcus aureus 15 (31.9%), Staphylococcus saprophyticus 8 (17.02%), Staphylococcus epidermidis 6 (12.76%), Enterococcus faecalis 5 (10.6%), Escherichia coli 9 (19.14%), Klebsiella sps 4 (8.5%), Micrococci 3 (6.38%). Maximum cases were in second trimester 25 (53.19%) followed by 3rd trimester 15 (31.9%) and 1st trimester 7 (14.89%). Women with positive cultures were administered antibiotics for 1 week and pregnancy was uneventful. In women with ASB in the last trimester, 10 (58.82%) developed maternal complications, 5 (29.41%) premature rupture of membranes, 2 (11.76%) puerperal pyrexia, 3 (17.64%) Threatened preterm labour, 1 case of PTL (1.85%) and foetal complication of Low birth weight. 53 (53%) women who are culture negative were without any maternal and foetal complications.

  The present study concludes that undetected ASB leads to various maternal and foetal complications. Hence, it is mandatory to screen all antenatal women for ASB to initiate appropriate treatment so as to minimise maternal and foetal complications.

Keywords: Urinary Tract Infection (UTI); Asymptomatic Bacteriuria (ASB); Premature Rupture of Membranes; Low Birth Weight (LBW); Staphylococcus aureus

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References

  1. Rajshekhar D and Kerure. “Prevalence of Asymptomatic Bacteriuria among Pregnant women in a tertiary care hospital”. Journal of Scientific and Research Publications 3.11 (2013). 
  2. Girishbabu RJ., et al. “Asymptomatic bacteriuria in pregnancy”. International Journal of Biological and Medical Research 2.3 (2011): 740-742.
  3. B Prasanna., et al. “Prevalence of Asymptomatic Bacteriuria in Pregnant Women, Isolates and their Culture Sensitivity Pattern”. International Journal of Current Microbiology and Applied Sciences 4.8 (2015): 28-353.
  4. Kasinathan A and Thirumal Prasad. “Prevalence of asymptomatic bacteriuria in antenatal women attending a tertiary care hospital”. International Journal of Reproduction, Contraception, Obstetrics and Gynecology 3.2 (2014): 437-441.
  5. Sujatha R and Nawani M. “Prevalence of asymptomatic bacteriuria and its antibacterial susceptibility pattern among pregnant women attending the antenatal clinic at kanpur, India”. Journal of Clinical and Diagnostic Research 8.4 (2014): DC01-DC3. 
  6. Jain V., et al. “Asymptomatic bacteriuria and obstetric outcome following treatment in early versus late pregnancy in north Indian women”. Indian Journal of Medical Research 137 (2013): 753-758.
  7. Turpin C., et al. “Asymptomatic bacteriuria in pregnant women attending antenatal clinic at komfo anokye teaching hospital, kumasi, ghana”. Ghana Medical Journal 41.1 (2007): 26-29.
  8. M Anayet Ullah., et al. “Prevalence of asymptomatic bacteriuria and its consequences in pregnancy in a rural community of”.  Bangladesh Medical Research Council Bulletin 33 (2007): 60-64.
  9. Kerure SB., et al. “Asymptomatic bacteriuriaamong among pregnant women”. International Journal of Reproduction, Contraception, Obstetrics and Gynecology (2007).
  10. Imade PE., et al. “Asymptomatic bacteriuria among pregnant women”. North American Journal of Medicine and Science 2.6 (2010): 263-266.
  11. Schnarr J and F Smaill. “Asymptomatic bacteriuria and symptomatic urinery tract infections in pregnancy”. European Journal of Clinical Investigation 38.2 (2008): 52-57.
  12. Lavanya SV and Jogalokshmi D. “Asymptomatic bacteriuria in antenatal women”. International Journal of Medical Microbiology 20.2 (2002): 105-106.
  13. Neupane MS., et al. “Asymptomatic Bacteriuria among Pregnant Women attending the Outpatient Clinics of Chitwan Medical College teaching hospital in Chitwan, Nepal”. International Research Journal of Pharmacy 3.11 (2012): 78-80.
  14. Omoregie R., et al. “Observed changes in the prevalence of uropathogens in Benin City, Nigeria”. New Zealand Institute of Medical Laboratory Science 62 (2008): 29-31.
  15. Strom BL., et al. “Sexual activity, contraceptive use, and other risk factors for symptomatic and asymptomatic bacteriuria”. Annals of Internal Medicine 107 (1987): 816-823.
  16. Fihn SD., et al. “Use of spermicide coated condoms and other risk factors for urinary tract infection caused by Staphylococcus saprophyticus”. Archives of Internal Medicine 158 (1998): 281-287.
  17. Turpin CA., et al. “Asymptomatic bacteriuria in pregnant women at-tending antenatal clinic at komfo anokye teaching hospital, Kumasi”. Ghana Medical Journal 41.1 (2007): 26-29.
  18. Alghalibi SM., et al. “Bacterial urinary tract infection among pregnant women in Sana’a City-Yemen”. Arab Gulf Journal of Scientific Research 25 (2007): 23-31.
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Citation

Citation: D Sudhamadhuri., et al “Prevalence and Outcome of Asymptomatic Bacteriuria among Antenatal Women in a Tertiary Care Centre". Acta Scientific Microbiology 3.4 (2020): 118-122.



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