Acta Scientific Microbiology (ASMI) (ISSN: 2581-3226)

Review Article Volume 3 Issue 3

Influenza morbidity and mortality in Kerala: Hotspots that go unnoticed

Prabin Pradeep, Vidya Manju, Sathish Mundayoor and Mohammad Feraz Ahsan*

Centre for Communicable Diseases, Control and Prevention (Viral Research and Diagnostic Centre), Inter University Centre for Biomedical Research and Super Speciality Hospital, Kerala, India

*Corresponding Author: Mohammad Feraz Ahsan, Centre for Communicable Diseases, Control and Prevention (Viral Research and Diagnostic Centre), Inter University Centre for Biomedical Research and Super Speciality Hospital, Kerala, India. E-mail: feraz.niv@gmail.com

Received: February 17, 2020; Published: March 10, 2020

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Abstract

  Influenza viruses are a major health challenge faced by the global society; with the need for new vaccine every year and also the surfacing of antiviral resistance. Kerala has witnessed the occurrence of some zoonotic diseases in the past; there is presence of influenza A virus H1N1 in the state, but there is no proper data on any subtypes other than H1N1 from Kerala. The state is ecologically rich in forests, lakes, rivers and wildlife, resulting in mingling of many different species of animals and birds. Humans are at potential risk of getting infected from zoonotic viruses’ transmitted from the animal reservoir. This review tries to create a systemic data from the available data source on the presence of influenza virus in Kerala, also the status of the fauna of the state to identify the possible hotspots of viral spillover.

Keywords: Influenza Virus; Epidemiology; Kerala; Zoonotic Diseases; H1N1; Swine Flu

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References

  1. Shaw ML and Palese P. “Orthomyxoviridae”. In: Knipe, DM Howley, PM, editors Fields Virology 6th . Wolters Kluwer Health/Lippincott Williams and Wilkins (2013): 1151-1185. 
  2. Tong S., et al. “New world bats harbor diverse influenza A viruses”. PLoS Pathog 9.10 (2013): e1003657. 
  3. CDC. Flu Symptoms and Complications - CDC (2019).  
  4. Kilbourne ED. “Influenza pandemics of the 20th century”. Emerging Infectious Diseases. Centers for Disease Control and Prevention (CDC) 12 (2006): 9-14. 
  5. CDC. Past Pandemics | Pandemic Influenza (Flu) | CDC (2018). 
  6. Arbeitskreis Blut U “Bewertung BK. Influenza Virus”. Transfus Med Hemotherapy 36.1 (2009): 32-39. 
  7. Di Lella S., et al. “Modulation of the pH Stability of Influenza Virus Hemagglutinin: A Host Cell Adaptation Strategy”. Biophysical Journal. Biophysical Society 110 (2016):  2293-301. 
  8. OIE. What is Avian Influenza: OIE - World Organisation for Animal Health (2019). 
  9. World Health Organization. Human infection with avian influenza A(H7N9) virus - China (2015). 
  10. WHO. Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003-2019 (2019). 
  11. Shope RE. Swine Influenza: Iii. Filtration Experiments and Etiology”. Journal of Experimental Medicine 54.3 (1931): 373-85. 
  12. OIE. Swine Influenza Aetiology Epidemiology Diagnosis Prevention and Control References (2009). 
  13. Tu J., et al. “Isolation and molecular characterization of equine H3N8 influenza viruses from pigs in China”. Archives of Virology 154.5 (2009): 887-890. 
  14. Ma W., et al. “The pig as a mixing vessel for influenza viruses: Human and veterinary implications”. Journal of Molecular and Genetic Medicine 03.01 (2009). 
  15. CDC. Influenza in Cats | Seasonal Influenza (Flu) | CDC (2018). 
  16. Fiorentini L., et al. “Influenza A pandemic (H1N1) 2009 virus outbreak in a cat colony in Italy”. Zoonoses Public Health 58.8 (2011): 573-581. 
  17. Hatta M., et al. “Characterization of a feline influenza A(H7N2) virus”. Emerging Infectious Diseases 24.1 (2018): 75-86. 
  18. CDC. Key Facts about Canine Influenza (Dog Flu) | Seasonal Influenza (Flu) | CDC (2018). 
  19. Zhu H., et al. “Origins and Evolutionary Dynamics of H3N2 Canine Influenza Virus”. Journal of Virology 89.10 (2015): 5406-5418. 
  20. Voorhees IEH., et al. “Spread of canine influenza a(H3N2) virus, United States”. Emerging Infectious Diseases 23.12 (2017): 1950-1957. 
  21. Crawford PC., et al. “Epidemiology: Transmission of equine influenza virus to dogs”. Science 310.5747 (2005): 482-485. 
  22. Singh RK., et al. “A comprehensive review on equine influenza virus: Etiology, epidemiology, pathobiology, advances in developing diagnostics, vaccines, and control strategies. Frontiers in Microbiology”. Frontiers Media S.A. 9 (2018). 
  23. Reperant LA., et al. “Avian influenza viruses in mammals”. OIE Revue Scientifique et Technique 28.1 (2009): 137-159. 
  24. Shin DL., et al. “Highly pathogenic avian influenza A(H5N8) virus in gray seals, Baltic Sea”. Emerging Infectious Diseases 25.12 (2019): 2295-2298. 
  25. Campos ACA., et al. “Bat influenza a(HL18NL11) virus in fruit bats, Brazil”. Emerging Infectious Diseases 25.2 (2019): 333-337. 
  26. Alghamdi A., et al. “Molecular Evidence of Influenza A Virus Circulation in African Dromedary Camels Imported to Saudi Arabia, 2017-2018”. Open Forum Infectious Diseases 6.10 (2019). 
  27. Murakami S., et al. “Influenza D virus infection in dromedary camels, Ethiopia. Vol. 25, Emerging Infectious Diseases”. Centres for Disease Control and Prevention (CDC) (2019): 1224-1225. 
  28. Sreenivasan CC., et al. “Influenza a in bovine species: A narrative literature review. Viruses. MDPI AG 11 (2019). 
  29. O’Donovan T., et al. “Seroprevalence of influenza D virus in selected sample groups of Irish cattle, sheep and pigs”. Irish Veterinary Journal 72.1 (2019). 
  30. Quast M., et al. “Serological evidence for the presence of influenza D virus in small ruminants”. Veterinary Microbiology 180.3-4 (2015): 281-285. 
  31. Lvov DK., et al. “Comparison of influenza viruses isolated from man and from whales”. Bull World Bulletin of the World Health Organization 56.6 (1978): 923-930. 
  32. Hinshaw VS., et al. “Characterization of two influenza A viruses from a pilot whale”. Journal of Virology 58.2 (1986): 655-656. 
  33. Hall JS., et al. “Influenza infection in wild raccoons”. Emerging Infectious Diseases 14.12 (2008): 1842-1848. 
  34. Horimoto T., et al. “Highly pathogenic avian influenza virus infection in feral Raccoons, Japan”. Emerging Infectious Diseases 17.4 (2011): 714-717. 
  35. Li D., et al. “Influenza A(H1N1) pdm09 virus infection in giant pandas, China”. Emerging Infectious Diseases 20.3 (2014): 480-483. 
  36. Martelli P., et al. “Influenza A(H1N1) pdm09 virus infection in a Captive Giant Panda, Hong Kong”. Emerging Infectious Diseases 25.12 (2019): 2303-2306. 
  37. Boedeker NC., et al. “Pandemic (H1N1) 2009 influenza A virus infection associated with respiratory signs in sloth bears (Melursus ursinus)”. Zoonoses Public Health 64.7 (2017): 566-571. 
  38. Kerala | History, Map, Capital, and Facts | Britannica (2019). 
  39. Jones S., et al. “Evolutionary, genetic, structural characterization and its functional implications for the influenza A (H1N1) infection outbreak in India from 2009 to 2017”. Scientific Reports 9.1 (2017): 14690. 
  40. NCDC. State/UT - wise, Year-wise number of cases and deaths from 2012-2019: Ministry of Health and Family Welfare (2019). 
  41. Dayakar S., et al. “Comparative Study of Molecular Approaches for the Detection of Influenza Virus from Patient Samples Using Real-time PCR: Prospective Disease Burden Study in Kerala (India) from 2010 to 2016”. Current Infectious Disease Reports 20.8 (2018): 24. 
  42. OIE - World Organisation for Animal Health (2020). 
  43. Kumar M., et al. “Emergence of novel reassortant H6N2 avian influenza viruses in ducks in India”. Infection, Genetics and Evolution 61 (2018): 20-23. 
  44. Dubal ZB., et al. “Important Zoonotic Diseases: Prevention and Control Technical Bulletin ICAR Research Complex for Goa (Indian Council of Agricultural Research), Old Goa- 403 402, Goa, India 39 (2014).
  45. Kormuth KA., et al. “Environmental Persistence of Influenza Viruses Is Dependent upon Virus Type and Host Origin. Lowen AC, editor”. mSphere 4.4 (2019). 
  46. Wang C., et al. “Novel human H7N9 influenza virus in China”. Integrative Zoology 9.3 (2014): 372-375. 
  47. CDC. What You Should Know About Flu Antiviral Drugs | CDC (2019). 
  48. Hurt AC., et al. “Community Transmission of Oseltamivir-Resistant A(H1N1) pdm09 Influenza”. N The New England Journal of Medicine 365.26 (2011): 2541-2542. 
  49. Akram M., et al. “Antiviral potential of medicinal plants against HIV, HSV, influenza, hepatitis, and coxsackievirus: A systematic review”. Phyther Research 32.5 (2018): 811-822. 
  50. Pradeep P., et al. “Antiviral Potency of Mushroom Constituents”. In: Medicinal Mushrooms. Singapore: Springer Singapore (2019): 275-297. 
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Citation

Citation: Pradeep P., et al. “Influenza morbidity and mortality in Kerala: Hotspots that go unnoticed". Acta Scientific Microbiology 3.4 (2020): 75-96.




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