Acta Scientific Microbiology (ASMI) (ISSN: 2581-3226)

Research Article Volume 3 Issue 2

Radioactive Sediment-Induced Hypertension and Cancer Risk ; Possible Modification by Podophyllum Peltatum Leaf Extract

Tugbobo OS1*, Aluko BT2, Idowu KS3, Fayose TS4 and Babatola LJ4

1Department of Science Technology, Biochemistry Unit, Federal Polytechnic, Ado-Ekiti, Nigeria, West Africa
2Department of Biochemistry, Ekiti State University, Ado-Ekiti, Nigeria, West Africa
3Department of Mathematics and Statistics, Federal Polytechnic, Ado-Ekiti, Nigeria, West Africa
4Department Chemical Sciences, Joseph Ayo Babalola University, Ikejiarakeji, Nigeri, West Africa

*Corresponding Author: Tugbobo OS, Department of Science Technology, Biochemistry Unit, Federal Polytechnic, Ado-Ekiti, Nigeria, West Africa.

Received: January 04, 2020; Published: January 28, 2020



  Effluents due to local and unprotective mining activities can elevate concentration of primordial radionuclides and thus pose serious health threat to population of people living in the mining environment. The effect of the mining activities in the studied areas so far has been an environmental concern. Stream water, well-water and water sediments were collected around local mining area of Ijero-Ekiti, Ijero local government area in Ekiti State Nigeria. The activity concentration of the radionuclides were measured with gamma ray spectroscopy (GRS). The results of activity concentration of radionuclides obtained as mean activity concentration of plutonium 242Pu, uranium 238U and thorium 232Th in water sediments from dug wells are 1208.8 ± 216.6, 58.7 ± 6.7 and 117.1 ± 94.9 Bq l-1 respectively which are significantly (P < 0.05) higher than that obtained from dug well-water (262.2 ± 18.7, 16.5 ± 1.0 and 17.2 ± 1.8 Bq l-1) and earth surface stream water (226.3 ± 18.5, 14.5 ± 1.9 and 14.8 ± 1.5 Bq l-1) respectively in same location. The results from this study suggest that effluents from local mining activities may have elevated the activity of primordial radionuclides in the study area and this potends high cancer and hypertension risk for the entire populace. However, antioxidant and anticlastogenic properties exhibited by Podophyllum peltatum plant in this study could possibly justify the plant as dietary supplement to salvage the health risks in local mining areas.

Keywords: Cr (VI); Detoxification Mechanisms; Ps. aeruginosa 4442



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Citation: Tugbobo OS., et al. “Radioactive Sediment-Induced Hypertension and Cancer Risk ; Possible Modification by Podophyllum Peltatum Leaf Extract". Acta Scientific Microbiology 3.2 (2020): 110-114.


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