Abstract

  There are many medicinal plants which are having therapeutic potentials. Nigella sativa, commonly known as ‘Kalonji’ or ‘black cumin’ is a herbaceous plant which grows in Mediterranean countries but has been cultivated into other parts of the world. In the religion of Islam, it is considered as the greatest forms of healing medicine available. Prophet Muhammad (Peace be upon him) once stated that the Kalonji (Nigella sativa) can treat every disease -- except death (Sahih Bukhari 71:592). There are many biological activities of Nigella sativa which are reported in recent years including antioxidant, anti-inflammatory, anticancer and antibacterial, anti-diabetic, antifungal and many more. Plethora of studies have been carried out by researchers by using different seed extracts from Nigella sativa for antibacterial, antifungal, anti-mycetoma activities. Madurella mycetomatis is the commonest causative organism causing Eumycetoma and Streptomyces somaliensis is the commonest organism causing actinomycetoma [2]. In general, the current treatment for mycetoma is expensive and unsatisfactory. It needs a long duration, and has many side effects [3]. If drugs not effective and bone is infected, amputate the limb or debride tissue and continue treatment up to years.

  The present review is an effort to provide a detailed survey of the literature on scientific researches of anti-bacterial, anti-fungal and anti-mycetoma activities of the chloroform, ethanol and methanol extracts of Nigella sativa seed in vitro against bacterial strains of Staphylococcus Aureus, Proteus Vulgaris, Escherichia coli. , Fungal strains of Candida albicans, Aspergillus flavus and the organism Madurella mycetomatis of mycetoma.

Keywords: Nigella Sativa; Black Cumin; Kalonji; Mycetoma

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Citation

Citation: JK Oberoi and Tooba Momin. “Antibacterial, Antifungal, Antimycetoma Activities of Nigella Sativa". Acta Scientific Microbiology 3.2 (2020): 23-27.

Copyright

Copyright: © 2020 JK Oberoi and Tooba Momin. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.