Acta Scientific Microbiology (ISSN: 2581-3226)

Research Artilce Volume 3 Issue 1

Clinic, Epidemiology and Diagnosis of Human Echinococcosis

Eftychios Vittorakis, Petrica Ciobanca, Constantea Nicolae, Evangelos Vittorakis and Lia Monica Junie*

University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj Napoca, Romania Department of Microbiology, Cluj Napoca, Romania

*Corresponding Author: Lia Monica Junie, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj Napoca, Romania Department of Microbiology, Cluj Napoca, Romania.

Received: October 09, 2019; Published: December 04, 2019

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Abstract

 Cystic echinococcosis or hydatidosis is an infestation caused by the larval form of E. granulosus species. It may develop asymptomatically or as a severe disease, often fatal, in humans.

Objective: Our study is aimed to realize a radiography of the cases with hydatic cyst (and others form of presentation of the echinococcus infection), which were hospitalized at the regional institute of gastroenterology and hepatology (IRGH) Cluj Napoca, on a considerable period of time (5 years). 192 of cases with the diagnosis of Echinococcus spp. were hospitalized on the period of the 5 years establish to evaluate in our study. Women’s number (90) was higher as the men cases (80), Hydatidosis is more common in females, being present in 55 women (55%), than in males (45%), with small differences between different age groups. Patients with the age between 21 and 60 years old have summed almost 75% of the cases, which also represent the period of age when the persons can be most active in the professional jobs. Most of the patients were potentially economically active persons (taking into account workers and unemployed and even the students). From a total of 23 Romanian residence counties, the majority of the patients (53, approximately 30%) are from Cluj county, in which is also located the hospital from where the cases origin. Most frequently the E. granulosus species was involved, and in a considerable part the species remained unspecified. Surgery was the primary option of treatment in our casuistry with various type of procedures, most frequently cysto-pericystectomy and drainage. It can be seen that the number of cases in the of each year of the 5 years was relative constant, with little variations, which can indicate the lacking of preventive measures or an insufficiency of it or even the existence of a inherent risk despite of all the measured which were taken.

Conclusions: This study offers a pretty faithful image of the current situation about the Echinococcus infection pathology in the Transilvania area, on the period we had evaluated. Hydatidosis can be considered hence endemic on this region and means of prevention and control are still required to be introduced till the elimination of this parasitosis. Encouraging it’s the fact that means which have been proven efficient both in the treatment and most important in the primary prevention of this disease are largely available.

Keywords: Hydatid Cyst In Human; Hydatidosis; Human Echinococcosis; Hospitalized Patients; Diagnosis; Clinical Evolution; Serodiagnosis; Therapy

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References

  1. Eckert J., et al. “Geographic distribution and prevalence”. In: Eckert, J., M. A. Gemmell, F. X. Meslin, Z. S, Pawlowski Eds., WHO/OIE manual on echinococcosis in humans and animals: a public health problem of global concern, WHO Collaborating Centre for Parasitic Zoonoses, Institute of Parasitology, Veterinary and Medical Faculty, University of Zurich, Winterthurerstr. 266a, CH-8057 Zurich, Switzerland (2002).
  2. Bourée P. “Hydatidosis: dynamics of transmission”. World Journal of Surgery 25 (2001): 4-9.
  3. Romig T., et al. “The present situation of echinococcosisn in Europe”. Parasitology International 55 (2006): 187-191.
  4. Thompson RCA. “The taxonomy, phylogeny and transmission of Echinococcus”. Experimental Parasitology (2008): 439-446.
  5. Antonio D'Alessandro., et al. “New Aspects of Neotropical Polycystic (Echinococcus vogeli) and Unicystic (Echinococcus oligarthrus) Echinococcosis”. Clinical Microbiology Reviews 2 (2008): 380-401.
  6. Abu-Eshy SA. “Clinical characteristics, diagnosis and surgical management of hydatid cysts”. West African Journal of Medicine 2 (2006):14452.
  7. Connolly Stephanie. Echinococcosis. (2006).
  8. Howorth MB. "Echinococcosis of Bone”. Journal of Bone and Joint Surgery (1945): 401-411.
  9. Gherman I., et al. “Două boli parazitare grave: trichineloza şi chistul hidatic, Ed. ALL, Bucureşti, (1994): 7981.
  10. Ionescu V and Nicolae Ş. “Orientări în programul naţional de supraveghere, diagnostic şi combatere a parazitozoonozelor în România. Revista Română de Parazitologie, iunie (1995): 3839.
  11. Eckert J. “Alveolar echinococcosis (Echinococcus multilocularis) and other forms of echinococcosis (E.oligarthrus and E.vogeli). In: Zoonoses (S.R. Palmer, E.J.L. Soulsby and D.I.H. Simpson, eds). Oxford University Press, Oxford, (1998): 689-716.
  12. Tirnea L., et al. “Epidemiological and medico-social aspects of human hydatidosis in Timis County, Romania”. International Journal of Hygiene and Environmental Health (Romania) 59 (2009): 26-35.
  13. Thompson RCA and McManus DP. “Aetiology: parasites and life cycles”. In: Eckert J. et al. Manual on Echinococcosis in Humans and Animals: a Public Health Problem of Global Concern. WHO / OIE, Paris. World Health Organization, Geneva (2001): 1-19.
  14. Tashani OA., et al. “Epidemiology and strain characteristics of Echinococcus granulosus in the Benghazi area of eastern Libya”. Annals of Tropical Medicine and Parasitology 96 (2002): 369-381.
  15. Aboudaya MA. “Prevalence of Echinococcus granulosus among domestic animals in Libya”. Tropical Animal Health and Production 17 (1985): 169-170.
  16. Hosseini SV., et al. “In vitro protoscolicidal effects of hypertonic glucose on protoscolices of hydatid cyst”. The Korean Journal of Parasitology 3 (2006): 239-242.
  17. Thompson C. “The Biology of Echinococcus and Hydatid Disease”. London: George Allen and Unwin (1986).
  18. Morris D and K Richards. “Hydatid Disease: Current Medical and Surgical Management. Butterworth-Heinemann, Ltd.: Oxford (1992).
  19. Benosman F. “Considerations epidemiologique sur l` hydatidose animals en Tunisie”. Archives de l` Institue Pasteur”. Tunis 3-4 (1965): 409-418.
  20. https://www.google.ro/search?q=Hydatid+cysts&source
  21. David J Morseth. “Fine Structure of the Hydatid Cyst and Protoscolex of Echinococcus granulosus”. The Journal of Parasitology2 (1967): 312-325.
  22. Eckert J and Deplazes P. “Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern”. Clinical Microbiology Reviews 1 (2004):107-135.
  23. https://en.wikipedia.org/wiki/File:Cotton_rat_infected_with_Echinococcus_ multilocularis.jpg
  24. F Derbel., et al. “Hydatid Cysts of the Liver-Diagnosis”. Complications and Treatment, Abdominal Surgery, Prof. Fethi Derbel (Ed.), InTech, (2012).
  25. Mitrea LI. Boli parazitare la animale, Ed. Ceres Bucureşti (2002).
  26. Dan Steriu. “Infectii produse de helminti”. In Infectii parazitare. ILEX, Romania ed. (2003): 171-183.
  27. https://www.google.ro/search?q=Echinococcus+granulosus+life+cycle
  28. Junie M and Sasca C. “Parazitologie medicala”. Helmintologie Medicala (1994): 89-98.
  29. Junie M CI Saşcă. “Infecţii parazitare umane”. Ed.Dacia, ISBN 973-35-0642-7, iunie (1997).
  30. Lia Monica Junie., et al. “The actual situation of operated hydatic cyst in Cluj Napoca”. Journal of Parasitology1 (1998): 18 - 20.
  31. Lia Monica Junie., et al. Epidemiological aspects on hydatidosis in Cluj-Napoca Romanian Review of Parasitology, ISSN 1221-1796; 10.1 (2000): 8-11.
  32. Lia Monica Junie and Manuela Mihalache. The hydatic chist: a major problem of public health Dento Medica (Revue d’odontostomatologie de Sibiu, Edited by the Romanian-French Odonto-Stomatologic association), ISSN 1453-2476157 (2001): 8-10.
  33. Ciobanca Petrică Teofil and Lia Monica Junie. Diagnosis confirmation of human cystic echinococcosis by imagistic methods and immunoserological determinations Scientia Parasitologica 12.3 (2011): 151-161. 
  34. Ciobanca P and Lia Monica Junie. “Serological diagnosis and its applicability to the prophylaxis and therapy of hydatid cyst in human patients”. Sciencia Parasitologica 12 (2011): 39-46.
  35. Eckert J., et al. “WHO/OIE Manual on Echinococcosis in Humans and Animals: a Public Health Problem of Global Concern. World Organisation for Animal Health (Office International des Epizooties) and World Health Organization, 2001, Reprinted: (2002): 286.
  36. McManus DP. “Echinococcuswith particular reference to Southeast Asia”. Parasitol. 72 (2014): 267-303.
  37. Torgerson PR and Heath DD. "Transmission dynamics and control options for Echinococcus granulosus". Parasitology7 (2003): 143-158.
  38. Romig T., et al. “The present situation of echinococcosis in Europe”. Parasitology International 55 (2006): 187-191.
  39. Canda MS., et al. “The Pathology of Echinococcosis and the Current Echinococcosis Problem in Western Turkey (PDF)”. Turkish Journal of Medical Sciences 33 (2003): 369-374.
  40. Bitton M., et al. “Anaphylactic shock after traumatic rupture of a splenic echinococcal cyst”. Harefuah (in Hebrew).4 (1992): 226-228.
  41. Bratucu E and Ungureanu D. “Abcese hepatice”. Chistul hidatic. Chirurgie General?, sub redactia N. Angelescu ?i P. D.   Ed. Medical?”. Bucuresti (2000).
  42. Tappe D., et al. “Emergence of polycystic neotropical echinococcosis". Emerging Infectious Diseases 2 (2008): 292-297.
  43. Menghi CI., et al. “Pulmonary hydatidosis from Southern Argentina”. Trop Parasitol2 (2015):118-119.
  44. Sarkari B., et al. “Human cystic echinococcosis in Yasuj District in Southwest of Iran: an epidemiological study of seroprevalence and surgical cases over a ten-year period”. Zoonoses Public Health2 (2010):146-150.
  45. Celik M., et al. “Surgical treatment of pulmonary hydatid disease in children: report of 122 cases”. Journal of Pediatric Surgery 12 (2000): 1710-1713.
  46. Murtaza B., et al. “Massie splenic hydatid cyst”. JCPSP9 (2005): 568-570.
  47. Andronikou S., et al. “Classic and unusual appearances of hydatid disease in children”. Pediatric Radiology 32 (2002): 817-828.
  48. Ray M., et al. “Primary multiple intracerebral echinococcosis in a young child”. Journal of Tropical Pediatrics 1 (2001): 59-61.
  49. Benjelloun S and Elmrini M. "Le kyste hydatique du rein (a propos de 45 cas)". Progrès en Urologie 2 (1993): 209-215.
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Citation

Citation: Lia Monica Junie., et al. “Clinic, Epidemiology and Diagnosis of Human Echinococcosis".Acta Scientific Microbiology 3.1 (2020): 13-21.




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