Acta Scientific Microbiology

Research ArticleVolume 1 Issue 7

Antibacterial Effect of Carica papaya Root Extract on Some Selected Pathogens from Clinical Isolates

Wemambu II*, Ajose DJ and Eni CC and Suliman M Hussein

Department of Biological Sciences, College of Natural and Applied Sciences, Bells University of Technology, Ota, Ogun State, Nigeria

*Corresponding Author: Wemambu II, Department of Biological Sciences, College of Natural and Applied Sciences, Bells University of Technology, Ota, Ogun State, Nigeria.

Received: April 14, 2018; Published: June 05, 2018

Citation: Wemambu II., et al. "Antibacterial Effect of Carica papaya Root Extract on Some Selected Pathogens from Clinical Isolates" Acta Scientific Microbiology 1.7 (2018).

Abstract

Introduction: The search for alternate sources of antibiotics to combat the growing global challenge of antibiotic resistance is imperative thus this study was designed to determine the antibacterial activity of Carica papaya root extract on Klebsiella species, Escherichia coli, Salmonella species, Pseudomonas species and Staphylococcus aureus.

Materials and Method: Dried and pulverized papaya roots were mixed with extraction solvents (water and ethanol). Aseptically the extracts were filtered and inoculated into Nutrient agar to ascertain sterility of the solutions.

Results: Results showed high antibacterial activity for ethanol extract and the cold-water extract of Carica papaya with ethanol extract having more effect. It was observed that the extract was effective against the Gram- positive and Gram-negative test organisms investigated while the Antibiotic susceptibility test revealed that the microorganisms were resistant to one or two of the antibiotics used (Ceftazidime (30 μg), Cefuroxime (30 μg), Gentamicin (10 μg), Ciprofloxacin (5 μg), Augmentin (50 μg), Nitrofurantoin (300 μg), Oflaxacin (5 μg), Ampicillin (10 μg) except for Escherichia coli which was resistant to all antibiotics used.

Conclusion:From the results obtained in this study, it can be inferred that Carica papaya root part is a potential source of natural therapeutic option that can be further exploited for the treatment of bacterial infection.

Keywords: Carica papaya; Antibacterial; Pathogenic Bacterial Isolates; Extracts

Copyright: © 2018 Wemambu Ifeoma Irene., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Member In






News and Events


  • Special Issue on Reviews
    Acta Scientific Journals has been started Special Issue on Reviews, researchers from world wide welcoming for submission of their reviews on any topic by on/ before August 30, 2019. Special Issue is going to be released on September 10, 2019
  • Submission Timeline for Regular Issue
    Last date for submission of articles is September 05, 2019.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US